Varaico: Literature-Extracted Genetic Variants

Gene:BMP1
Variant:p.E172D
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BMP1

NM_006129.5:p.E172D

Associated Papers

Stoichiometric transport of estrone 3-sulfate among genetic variants of OATP1A2 and OATP2B1 and structural analysis by molecular dynamics simulation: Impairment of gating mechanism in the unstable inward-open conformation of OATP2B1 (Asp215Val) significantly suppress the transport activity.

Akiyoshi T et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2025

Gene polymorphisms and thyroid hormone signaling: implication for the treatment of hypothyroidism.

Penna GC et al.

Endocrine, 2024

Comparison of the transport kinetics of fexofenadine and its pH dependency among OATP1A2 genetic variants.

Han H et al.

Drug Metabolism and Pharmacokinetics, 2022

Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.

Araki N et al.

Drug Metabolism and Pharmacokinetics, 2022

Thyroid Hormone Transporters.

Groeneweg S et al.

Endocrine Reviews, 2020

Genetic variability and population diversity of the human SLCO (OATP) transporter family.

Zhang B et al.

Pharmacological Research, 2019

Functional analysis of novel polymorphisms in the human SLCO1A2 gene that encodes the transporter OATP1A2.

Zhou F et al.

The Aaps Journal, 2013

Primary and secondary thyroid hormone transporters.

Kinne A et al.

Thyroid Research, 2011

Implications of genetic polymorphisms in drug transporters for pharmacotherapy.

Kerb R

Cancer Letters, 2006

Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry.

Lee W et al.

The Journal of Biological Chemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."