Varaico: Literature-Extracted Genetic Variants

Gene:BMP15
Variant:p.L3L
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BMP15

NM_005448.2:p.L3L

Associated Papers

Pharmacogenetic analysis using artificial intelligence (AI) to identify polymorphisms associated with sub-optimal ovarian response and hyper-response.

Ortiz JA et al.

Journal of Assisted Reproduction and Genetics, 2025

Association between TGF-β/BMP signaling pathway polymorphisms and the risk of primary ovarian insufficiency in Korean women.

Ha YH et al.

Genes & Genomics, 2024

HNF1A gene mutations and premature ovarian failure (POF): evidence from a clinical paradigm combining MODY 3 and POF.

Xekouki P et al.

Hormones (athens, Greece), 2024

Implication of Novel BMP15 and GDF9 Variants in Unexpected Poor Ovarian Response.

Mehdizadeh A et al.

Reproductive Sciences (thousand Oaks, Calif.), 2024

Current understanding of the genomic abnormities in premature ovarian failure: chance for early diagnosis and management.

Yang X et al.

Frontiers in Medicine, 2023

The landscape of genetic variations in non-syndromic primary ovarian insufficiency in the MENA region: a systematic review.

Allouch A et al.

Frontiers in Endocrinology, 2023

A systematic review and standardized clinical validity assessment of genes involved in female reproductive failure.

Volozonoka L et al.

Reproduction (cambridge, England), 2022

35451369 (PubMed )
Supplement: supplementary_table_1.xlsx › S1

Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency.

Afkhami F et al.

Reproductive Biology and Endocrinology : Rb&e, 2022

Association of FSHR, LH, LHR, BMP15, GDF9, AMH, and AMHR polymorphisms with poor ovarian response in patients undergoing in vitro fertilization.

Meireles AJC et al.

Jbra Assisted Reproduction, 2021

Follicle-stimulating hormone receptor gene polymorphisms of ovarian reserve markers in Romanian population.

Tănase AE et al.

Experimental and Therapeutic Medicine, 2020

Genome-Wide Identification of a Regulatory Mutation in BMP15 Controlling Prolificacy in Sheep.

Chantepie L et al.

Frontiers in Genetics, 2020

Association of BMP15 and GDF9 variants to premature ovarian insufficiency.

Santos M et al.

Journal of Assisted Reproduction and Genetics, 2019

Use of Bone Morphogenetic Protein 15 Polymorphisms to Predict Ovarian Stimulation Outcomes in Infertile Brazilian Women.

Peluso C et al.

Genetic Testing and Molecular Biomarkers, 2017

Mutation analysis of exon1 of bone morphogenetic protein-15 gene in Iranian patients with polycystic ovarian syndrome.

Mehdizadeh A et al.

International Journal of Reproductive Biomedicine, 2016

NOBOX is a strong autosomal candidate gene in Tunisian patients with primary ovarian insufficiency.

Bouali N et al.

Clinical Genetics, 2016

A novel FOXL2 gene mutation and BMP15 variants in a woman with primary ovarian insufficiency and blepharophimosis-ptosis-epicanthus inversus syndrome.

Settas N et al.

Menopause (new York, N.y.), 2015

Single nucleotide polymorphisms in premature ovarian failure-associated genes in a Chinese Hui population.

Ma L et al.

Molecular Medicine Reports, 2015

A single nucleotide polymorphism of bone morphogenic protein-15 is not associated with ovarian reserve or response to ovarian stimulation.

Cerra C et al.

Human Reproduction (oxford, England), 2014

BMP15 c.-9C>G promoter sequence variant may contribute to the cause of non-syndromic premature ovarian failure.

Fonseca DJ et al.

Reproductive Biomedicine Online, 2014

Gene variation and premature ovarian failure: a meta-analysis.

Pu D et al.

European Journal of Obstetrics, Gynecology, and Reproductive Biology, 2014

Associations between Individual and Combined Polymorphisms of the TNF and VEGF Genes and the Embryo Implantation Rate in Patients Undergoing In Vitro Fertilization (IVF) Programs.

Boudjenah R et al.

Plos One, 2014

Genetic polymorphisms influence the ovarian response to rFSH stimulation in patients undergoing in vitro fertilization programs with ICSI.

Boudjenah R et al.

Plos One, 2012

Invited commentary: a single nucleotide polymorphism in BMP15 is associated with high response to controlled ovarian hyperstimulation.

Abir R et al.

Reproductive Biomedicine Online, 2011

A single nucleotide polymorphism in BMP15 is associated with high response to ovarian stimulation.

Hanevik HI et al.

Reproductive Biomedicine Online, 2011

Variants of the BMP15 gene in a cohort of patients with premature ovarian failure.

Tiotiu D et al.

Human Reproduction (oxford, England), 2010

Association of genetic markers within the BMP15 gene with anovulation and infertility in women with polycystic ovary syndrome.

Gónzalez A et al.

Fertility and Sterility, 2008

BMP15 mutations in XX gonadal dysgenesis and premature ovarian failure.

Ledig S et al.

American Journal of Obstetrics and Gynecology, 2008

Bone morphogenetic protein 15 (BMP15) alleles predict over-response to recombinant follicle stimulation hormone and iatrogenic ovarian hyperstimulation syndrome (OHSS).

Morón FJ et al.

Pharmacogenetics and Genomics, 2006

Missense mutations in the BMP15 gene are associated with ovarian failure.

Dixit H et al.

Human Genetics, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."