Associated Papers
Exploring the functional and structural impacts of high-risk nsSNPs in human BMP15 and GDF9 genes associated with premature ovarian failure: an in silico approach.
Navapour L et al.
Journal of Biomolecular Structure & Dynamics, 2025
From Dominant Assumptions to Recessive Trait: Rethinking BMP15 in Ovarian Dysfunction.
Hervé B et al.
Reproductive Sciences (thousand Oaks, Calif.), 2025
Association of Polymorphisms in FSHR, ESR1, and BMP15 with Primary Ovarian Insufficiency and Meta-Analysis.
Lee JY et al.
Diagnostics (basel, Switzerland), 2024
Understanding the Mechanisms of Diminished Ovarian Reserve: Insights from Genetic Variants and Regulatory Factors.
Zhu Q et al.
Reproductive Sciences (thousand Oaks, Calif.), 2024
Screening for causative mutations in ovine BMPR1B and BMP15 genes and their homologous fragments in human.
Zamani P et al.
Journal of Assisted Reproduction and Genetics, 2023
Current understanding of the genomic abnormities in premature ovarian failure: chance for early diagnosis and management.
Yang X et al.
Frontiers in Medicine, 2023
Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency.
Afkhami F et al.
Reproductive Biology and Endocrinology : Rb&e, 2022
Lysine acetylation regulates the interaction between proteins and membranes.
Okada AK et al.
Nature Communications, 2021
Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice.
Jiao SY et al.
Human Reproduction Update, 2021
Fundamental role of BMP15 in human ovarian folliculogenesis revealed by null and missense mutations associated with primary ovarian insufficiency.
Rossetti R et al.
Human Mutation, 2020
The Genetics of Non-Syndromic Primary Ovarian Insufficiency: A Systematic Review.
Venturella R et al.
International Journal of Fertility & Sterility, 2019
Association of BMP15 and GDF9 variants to premature ovarian insufficiency.
Santos M et al.
Journal of Assisted Reproduction and Genetics, 2019
Systematic analysis of the intersection of disease mutations with protein modifications.
Simpson CM et al.
Bmc Medical Genomics, 2019
High-resolution array-CGH analysis on 46,XX patients affected by early onset primary ovarian insufficiency discloses new genes involved in ovarian function.
Bestetti I et al.
Human Reproduction (oxford, England), 2019
BMP15 Mutations Associated With Primary Ovarian Insufficiency Reduce Expression, Activity, or Synergy With GDF9.
Patiño LC et al.
The Journal of Clinical Endocrinology and Metabolism, 2017
Genetics of primary ovarian insufficiency.
Rossetti R et al.
Clinical Genetics, 2017
Aetiological coding sequence variants in non-syndromic premature ovarian failure: From genetic linkage analysis to next generation sequencing.
Laissue P
Molecular and Cellular Endocrinology, 2015
BMP15 c.-9C>G promoter sequence variant may contribute to the cause of non-syndromic premature ovarian failure.
Fonseca DJ et al.
Reproductive Biomedicine Online, 2014
Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep.
Demars J et al.
Plos Genetics, 2013
Gene mutations associated with anomalies of human gonad formation.
Bashamboo A et al.
Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation, 2013
Positive selection in bone morphogenetic protein 15 targets a natural mutation associated with primary ovarian insufficiency in human.
Auclair S et al.
Plos One, 2013
Mutations in inhibin and activin genes associated with human disease.
Shelling AN
Molecular and Cellular Endocrinology, 2012
Haplotype and mutation analysis of the TGFBR3 gene in Chinese women with idiopathic premature ovarian failure.
Qin CR et al.
Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, 2012
Invited commentary: a single nucleotide polymorphism in BMP15 is associated with high response to controlled ovarian hyperstimulation.
Abir R et al.
Reproductive Biomedicine Online, 2011
Integral role of GDF-9 and BMP-15 in ovarian function.
Otsuka F et al.
Molecular Reproduction and Development, 2011
Genes involved in human premature ovarian failure.
Persani L et al.
Journal of Molecular Endocrinology, 2010
Variants of the BMP15 gene in a cohort of patients with premature ovarian failure.
Tiotiu D et al.
Human Reproduction (oxford, England), 2010
Genes governing premature ovarian failure.
Dixit H et al.
Reproductive Biomedicine Online, 2010
BMP15 and premature ovarian failure: causal mutations, variants, polymorphisms?
Lakhal B et al.
Clinical Endocrinology, 2010
A novel BMP15 variant, potentially affecting the signal peptide, in a familial case of premature ovarian failure.
Lakhal B et al.
Clinical Endocrinology, 2009
Bone morphogenetic protein 15 (BMP15) acts as a BMP and Wnt inhibitor during early embryogenesis.
Di Pasquale E et al.
The Journal of Biological Chemistry, 2009
Primary Ovarian Insufficiency: X chromosome defects and autoimmunity.
Persani L et al.
Journal of Autoimmunity, 2009
BMP15 mutations associated with primary ovarian insufficiency cause a defective production of bioactive protein.
Rossetti R et al.
Human Mutation, 2009
Variation in bone morphogenetic protein 15 is not associated with spontaneous human dizygotic twinning.
Zhao ZZ et al.
Human Reproduction (oxford, England), 2008
Association of genetic markers within the BMP15 gene with anovulation and infertility in women with polycystic ovary syndrome.
Gónzalez A et al.
Fertility and Sterility, 2008
Recent advances in the study of genes involved in non-syndromic premature ovarian failure.
Laissue P et al.
Molecular and Cellular Endocrinology, 2008
BMP15 mutations in XX gonadal dysgenesis and premature ovarian failure.
Ledig S et al.
American Journal of Obstetrics and Gynecology, 2008
Recent developments in identifying genetic determinants of premature ovarian failure.
Skillern A et al.
Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation, 2008
A novel mutation in the bone morphogenetic protein 15 gene causing defective protein secretion is associated with both increased ovulation rate and sterility in Lacaune sheep.
Bodin L et al.
Endocrinology, 2007
Mutational analysis of betaglycan/TGF-betaRIII in premature ovarian failure.
Chand AL et al.
Fertility and Sterility, 2007
Sequence variants in exons of the BMP-15 gene in Chinese patients with premature ovarian failure.
Zhang P et al.
Acta Obstetricia Et Gynecologica Scandinavica, 2007
Mutational analysis of BMP15 and GDF9 as candidate genes for premature ovarian failure.
Chand AL et al.
Fertility and Sterility, 2006
Bone morphogenetic protein 15 (BMP15) alleles predict over-response to recombinant follicle stimulation hormone and iatrogenic ovarian hyperstimulation syndrome (OHSS).
Morón FJ et al.
Pharmacogenetics and Genomics, 2006
Identification of new variants of human BMP15 gene in a large cohort of women with premature ovarian failure.
Di Pasquale E et al.
The Journal of Clinical Endocrinology and Metabolism, 2006
Missense mutations in the BMP15 gene are associated with ovarian failure.
Dixit H et al.
Human Genetics, 2006
Mutations and sequence variants in GDF9 and BMP15 in patients with premature ovarian failure.
Laissue P et al.
European Journal of Endocrinology, 2006
Molecular biology and physiological role of the oocyte factor, BMP-15.
Moore RK et al.
Molecular and Cellular Endocrinology, 2005
Hypergonadotropic ovarian failure associated with an inherited mutation of human bone morphogenetic protein-15 (BMP15) gene.
Di Pasquale E et al.
American Journal of Human Genetics, 2004
Genetics of primary ovarian insufficiency: new developments and opportunities.
Qin Y et al.
Human Reproduction Update, 0