Varaico: Literature-Extracted Genetic Variants

Gene:BMPR1B
Variant:p.Q249R
Back to variants list

BMPR1B

NM_001203.3:p.Q249R

Associated Papers

Comprehensive Analysis of PAPPA2 Expression and Genetic Variants in Sheep and Their Association With Litter Size.

Wang Y et al.

Veterinary Medicine and Science, 2026

Whole-Genome Sequencing of Dorper × Hu Hybrid Sheep for Screening Selection Signatures Associated with Litter Size.

Qiao L et al.

Animals : an Open Access Journal From Mdpi, 2025

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S6

Fine mapping genetic variants affecting birth weight in sheep: a GWAS of 3007 individuals using low-coverage whole genome sequencing.

Li R et al.

Journal of Animal Science and Biotechnology, 2025

The Role of TGF-β Signaling Pathway in Determining Small Ruminant Litter Size.

Han Y et al.

Biology, 2025

Association of BMP15 and GDF9 Gene Polymorphisms with Litter Size in Hu Sheep.

Zhang Y et al.

Genes, 2025

Generation and propagation of high fecundity gene edited fine wool sheep by CRISPR/Cas9.

Zhang X et al.

Scientific Reports, 2025

Development and validation of a simple, cost-effective competitive allele-specific PCR assay for largescale screening and detection of FecB mutation in sheep.

Periasamy K et al.

Plos One, 2025

Transcription factor BRCA1 is associated with BMPR1B transcriptional activity in sheep ovarian granulosa cells.

Abdurahman A et al.

Frontiers in Veterinary Science, 2025

FecBB mutation enhances follicle stimulating hormone sensitivity of granulosa cells by up-regulating the SMAD1/5-USF1-FSHR signaling pathway.

Jiao Y et al.

International Journal of Biological Macromolecules, 2024

Genetic regulation of ovulation rate and multiple births.

Montgomery GW

Reproduction, Fertility, and Development, 2024

Single-cell RNA-seq reveals the effects of the FecB mutation on the transcriptome profile in ovine cumulus cells.

Guo X et al.

Scientific Reports, 2024

A repertoire of single nucleotide polymorphisms (SNPs) of major fecundity BMPR1B gene among 75 sheep breeds worldwide.

Cao C et al.

Theriogenology, 2024

Detection of Booroola Polymorphism of Bone Morphogenetic Protein Receptor 1b and Embrapa Polymorphism of Growth Differentiation Factor 9 in Sheep in Thailand.

Sae-Foo P et al.

Animals : an Open Access Journal From Mdpi, 2024

Integration analysis of pituitary proteome and transcriptome reveals fertility-related biomarkers in FecB mutant Small Tail Han sheep.

Wang X et al.

Frontiers in Endocrinology, 2024

Association analysis of single nucleotide polymorphisms in the sheep FecB gene with reproductive and body size performance.

Kong L et al.

Archives Animal Breeding, 2024

Expression profiles of oviductal mRNAs and lncRNAs in the follicular phase and luteal phase of sheep (Ovis aries) with 2 fecundity gene (FecB) genotypes.

Chen W et al.

G3 (bethesda, Md.), 2023

Proteomic Analysis Identifies Distinct Protein Patterns for High Ovulation in FecB Mutant Small Tail Han Sheep Granulosa Cells.

Wang X et al.

Animals : an Open Access Journal From Mdpi, 2023

FecB mutation and litter size are associated with a 90-base pair deletion in BMPR1B in East Friesian and Hu crossbred sheep.

Li D et al.

Animal Biotechnology, 2023

Polymorphisms in BMPRIB gene affect litter size in Chinese indigenous sheep breed.

Mo F et al.

Animal Biotechnology, 2023

Survey of the relationship between polymorphisms within the BMPR1B gene and sheep reproductive traits.

Akhatayeva Z et al.

Animal Biotechnology, 2023

Are Copy Number Variations within the FecB Gene Significantly Associated with Morphometric Traits in Goats?

Bi Y et al.

Animals : an Open Access Journal From Mdpi, 2022

BMPR-IB gene disruption causes severe limb deformities in pigs.

Yang Q et al.

Zoological Research, 2022

Association between novel variants in BMPR1B gene and litter size in Mongolia and Ujimqin sheep breeds.

Gao Y et al.

Reproduction in Domestic Animals = Zuchthygiene, 2021

Association of a genetic polymorphism in the BMPR-1B gene, and non-genetic factors with the natural prolificacy of the Colombian-haired sheep.

Medina-Montes A et al.

Tropical Animal Health and Production, 2021

Polymorphism Detection of GDF9 Gene and Its Association with Litter Size in Luzhong Mutton Sheep (Ovis aries).

Wang F et al.

Animals : an Open Access Journal From Mdpi, 2021

Novel indel variations of the sheep FecB gene and their effects on litter size.

Li H et al.

Gene, 2021

Transcriptome Analysis Reveals Differentially Expressed Genes and Long Non-coding RNAs Associated With Fecundity in Sheep Hypothalamus With Different FecB Genotypes.

Chen S et al.

Frontiers in Cell and Developmental Biology, 2021

An investigation of the effects of BMPR1B, BMP15, and GDF9 genes on litter size in Ramlıç and Dağlıç sheep.

Çelikeloğlu K et al.

Archives Animal Breeding, 2021

Detection of mRNA Expression and Copy Number Variations Within the Goat Fec B Gene Associated With Litter Size.

Bi Y et al.

Frontiers in Veterinary Science, 2021

Insight Into Pituitary lncRNA and mRNA at Two Estrous Stages in Small Tail Han Sheep With Different FecB Genotypes.

Chen S et al.

Frontiers in Endocrinology, 2021

Highly efficient generation of sheep with a defined FecBB mutation via adenine base editing.

Zhou S et al.

Genetics, Selection, Evolution : Gse, 2020

Eukaryotic expression, Co-IP and MS identify BMPR-1B protein-protein interaction network.

Jia J et al.

Biological Research, 2020

Mutations in NLRP5 and NLRP9 are Associated with Litter Size in Small Tail Han Sheep.

Zhang Z et al.

Animals : an Open Access Journal From Mdpi, 2020

Association of polymorphisms in bone morphogenetic protein receptor-1B gene exon-9 with litter size in Dorset, Mongolian, and Small Tail Han ewes.

Jia J et al.

Asian-australasian Journal of Animal Sciences, 2019

Smad4 Feedback Enhances BMPR1B Transcription in Ovine Granulosa Cells.

Abdurahman A et al.

International Journal of Molecular Sciences, 2019

Genetic polymorphisms of fecundity genes in Watish Sudanese desert sheep.

Mohamed SEI et al.

Veterinary World, 2019

Generation of gene-edited sheep with a defined Booroola fecundity gene (FecBB) mutation in bone morphogenetic protein receptor type 1B (BMPR1B) via clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) 9.

Zhou S et al.

Reproduction, Fertility, and Development, 2018

A novel indel within goat casein alpha S1 gene is significantly associated with litter size.

Wang K et al.

Gene, 2018

Using sheep genomes from diverse U.S. breeds to identify missense variants in genes affecting fecundity.

Heaton MP et al.

F1000research, 2017

Production of Transgenic Pigs with an Introduced Missense Mutation of the Bone Morphogenetic Protein Receptor Type IB Gene Related to Prolificacy.

Zhao X et al.

Asian-australasian Journal of Animal Sciences, 2016

Designing, optimization and validation of tetra-primer ARMS PCR protocol for genotyping mutations in caprine Fec genes.

Ahlawat S et al.

Meta Gene, 2014

Polymorphism and nucleotide sequencing of BMPR1B gene in prolific Assam hill goat.

Dutta R et al.

Molecular Biology Reports, 2014

Association of BMPR-1B and GDF9 genes polymorphisms and secondary protein structure changes with reproduction traits in Mehraban ewes.

Abdoli R et al.

Gene, 2013

Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep.

Demars J et al.

Plos Genetics, 2013

Screening of indigenous goats for prolificacy associated DNA markers of sheep.

Ahlawat S et al.

Gene, 2013

A missense mutation in growth differentiation factor 9 (GDF9) is strongly associated with litter size in sheep.

Våge DI et al.

Bmc Genetics, 2013

Genetic testing for phenotype-causing variants in sheep and goats.

Lühken G

Molecular and Cellular Probes, 2012

Missense mutations of the BMPR1B (ALK6) gene in childhood idiopathic pulmonary arterial hypertension.

Chida A et al.

Circulation Journal : Official Journal of the Japanese Circulation Society, 2012

1–50 of 65 papers
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."