Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.K601del1
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BRAF

NM_004333.6:p.K601del1

Associated Papers

Unveiling a rare BRAF mutation in minimally invasive follicular thyroid carcinoma: A case report.

Lee PS et al.

Medicine, 2024

Identification of a Novel Non-V600E BRAF Mutation in Papillary Thyroid Cancer.

Capezzone M et al.

Case Reports in Endocrinology, 2024

BRAF-Driven Pancreatic Cancer: Prevalence, Molecular Features, and Therapeutic Opportunities.

Ciner AT et al.

Molecular Cancer Research : Mcr, 2023

Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Asselta R et al.

Thoracic Cancer, 2021

33704917 (PubMed )
Supplement: TCA-12-1271-s003.xls › Foglio1

High sensitivity sanger sequencing detection of BRAF mutations in metastatic melanoma FFPE tissue specimens.

Cheng LY et al.

Scientific Reports, 2021

33907234 (PubMed )
Supplement: 41598_2021_88391_MOESM1_ESM.pdf

A Narrative Review of Genetic Alterations in Primary Thyroid Epithelial Cancer.

Romei C et al.

International Journal of Molecular Sciences, 2021

Negative reactions of BRAF mutation-specific immunohistochemistry to non-V600E mutations of BRAF.

Seto K et al.

Pathology International, 2020

Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.

Kim YS et al.

Bmc Urology, 2018

30064409 (PubMed )
Supplement: 12894_2018_380_MOESM1_ESM.xlsx › Supplementary_Table_1

Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract.

Lee JY et al.

Translational Oncology, 2018

29161613 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_1

The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes.

Pagan M et al.

Bmc Bioinformatics, 2016

26818556 (PubMed )
Supplement: 12859_2015_849_MOESM3_ESM.pdf

Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.

Lee JY et al.

Oncotarget, 2015

26527317 (PubMed )
Supplement: oncotarget-06-43731-s002.xlsx › Table_S1

A 3-bp Deletion VK600-1E in the BRAF Gene Detected in a Young Woman with Papillary Thyroid Carcinoma.

Dvorakova S et al.

Endocrine Pathology, 2015

Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA.

Izumchenko E et al.

Nature Communications, 2015

26374070 (PubMed )
Supplement: NIHMS713162-supplement-1.pdf

Molecular characterization of patients with pathologic complete response or early failure after neoadjuvant chemotherapy for locally advanced breast cancer using next generation sequencing and nCounter assay.

Park K et al.

Oncotarget, 2015

26009992 (PubMed )
Supplement: oncotarget-06-24499-s002.xlsx › Supplementary_Table_1

Pathogenetic Implications of BRAF Mutation Distribution in Stage IV Melanoma Patients.

Baiter M et al.

Dermatology (basel, Switzerland), 2015

Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas.

Tone AA et al.

Bmc Cancer, 2014

25523272 (PubMed )
Supplement: 12885_2014_5198_MOESM14_ESM.xlsx › Sheet1__2_

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

MacConaill LE et al.

The Journal of Molecular Diagnostics : Jmd, 2014

The clinical response to vemurafenib in a patient with a rare BRAFV600DK601del mutation-positive melanoma.

Trudel S et al.

Bmc Cancer, 2014

Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions.

Brannon AR et al.

Genome Biology, 2014

25164765 (PubMed )
Supplement: 13059_2014_454_MOESM1_ESM.xlsx › Sheet1

Sensitive allele-specific real-time PCR test for mutations in BRAF codon V600 in skin melanoma.

Pisareva E et al.

Melanoma Research, 2014

Prevalence, tumorigenic role, and biochemical implications of rare BRAF alterations.

Barollo S et al.

Thyroid : Official Journal of the American Thyroid Association, 2014

High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.

Kim S et al.

Plos One, 2014

25372287 (PubMed )
Supplement: pone.0111693.s003.xls › ion_ampliseq_cancer_panel_mutat

Rare BRAF mutations in melanoma patients: implications for molecular testing in clinical practice.

Heinzerling L et al.

British Journal of Cancer, 2013

Automated universal BRAF state detection within the activation segment in skin metastases by pyrosequencing-based assay U-BRAF(V600).

Skorokhod A et al.

Plos One, 2013

Identification of biomarkers to distinguish clear cell sarcoma from malignant melanoma.

Yang L et al.

Human Pathology, 2012

Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma.

Deshpande V et al.

Bmc Cancer, 2011

21303542 (PubMed )
Supplement: 1471-2407-11-60-S1.XLS › Table_1_OM3_core_sites

A minireview: the role of MAPK/ERK and PI3K/Akt pathways in thyroid follicular cell-derived neoplasm.

Brzezianska E et al.

Frontiers in Bioscience (landmark Edition), 2011

Recent advances in molecular diagnosis of thyroid cancer.

Legakis I et al.

Journal of Thyroid Research, 2011

Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma.

Santarpia L et al.

Cancer, 2010

BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications.

Tang KT et al.

Journal of the Chinese Medical Association : Jcma, 2010

Profiling critical cancer gene mutations in clinical tumor samples.

MacConaill LE et al.

Plos One, 2009

19924296 (PubMed )
Supplement: pone.0007887.s002.xls › Table_S1_

Targeting of the BRAF gene in papillary thyroid carcinoma (review).

Li Y et al.

Oncology Reports, 2009

High prevalence of BRAF mutation in a Brazilian cohort of patients with sporadic papillary thyroid carcinomas: correlation with more aggressive phenotype and decreased expression of iodide-metabolizing genes.

Oler G et al.

Cancer, 2009

Functional characterization of the novel T599I-VKSRdel BRAF mutation in a follicular variant papillary thyroid carcinoma.

De Falco V et al.

The Journal of Clinical Endocrinology and Metabolism, 2008

Seven-year follow-up of a juvenile female with papillary thyroid carcinoma with poor outcome, BRAF mutation and loss of expression of iodine-metabolizing genes.

Oler G et al.

Arquivos Brasileiros De Endocrinologia E Metabologia, 2008

Characterization of a novel complex BRAF mutation in a follicular variant papillary thyroid carcinoma.

Barzon L et al.

European Journal of Endocrinology, 2008

BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical implications.

Xing M

Endocrine Reviews, 2007

BRAF mutations in melanocytic lesions and papillary thyroid carcinoma samples identified using melting curve analysis of polymerase chain reaction products.

Hay R et al.

Archives of Pathology & Laboratory Medicine, 2007

Functional characterization of the T1799-1801del and A1799-1816ins BRAF mutations in papillary thyroid cancer.

Hou P et al.

Cell Cycle (georgetown, Tex.), 2007

Correlation between B-RAFV600E mutation and clinico-pathologic parameters in papillary thyroid carcinoma: data from a multicentric Italian study and review of the literature.

Fugazzola L et al.

Endocrine-related Cancer, 2006

Investigation of BRAF mutation in a series of papillary thyroid carcinoma and matched-lymph node metastasis reveals a new mutation in metastasis.

Oler G et al.

Clinical Endocrinology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."