Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.V600A
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BRAF

NM_004333.6:p.V600A

Associated Papers

Circulating tumor DNA profiling for non-invasive genomic analysis in Indian lung cancer patients: A real-world experience.

Jha P et al.

The Journal of Liquid Biopsy, 2025

40503459 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_S2

Multicenter In-House Evaluation of an Amplicon-Based Next-Generation Sequencing Panel for Comprehensive Molecular Profiling.

Jantus-Lewintre E et al.

Molecular Diagnosis & Therapy, 2025

39798063 (PubMed )
Supplement: 40291_2024_766_MOESM2_ESM.xlsx › S1c-Control_D_2_HD827

Spontaneous Necrosis of a High-Risk Bladder Tumor Under Immunotherapy for Concurrent Malignant Melanoma: Role of BRAF Mutations and PD-L1 Expression.

Condoiu C et al.

Biomedicines, 2025

Survey for Activating Oncogenic Mutation Variants in Metazoan Germline Genes.

Krueger KE

Journal of Molecular Evolution, 2024

Hotspot Exon 15 Mutations in BRAF Are Uncommon in Feline Tumours.

Kuroki K et al.

Veterinary and Comparative Oncology, 2024

Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma.

Pinto de Almeida N et al.

Clinical and Translational Medicine, 2024

39032005 (PubMed )
Supplement: CTM2-14-e1773-s009.docx

Targeted next-generation sequencing of 491 lung cancers in clinical practice: Implications for future detection strategy and targeted therapy.

Liu XD et al.

Heliyon, 2024

38496837 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Mining cancer genomes for change-of-metabolic-function mutations.

Tu KJ et al.

Communications Biology, 2023

37950065 (PubMed )
Supplement: 42003_2023_5475_MOESM2_ESM.pdf

Metastasising ameloblastoma or ameloblastic carcinoma? A case report with mutation analyses.

Hurník P et al.

Bmc Oral Health, 2023

Cutaneous Melanoma and Glioblastoma Multiforme Association-Case Presentation and Literature Review.

Orzan OA et al.

Diagnostics (basel, Switzerland), 2023

Electrochemical biosensors for analysis of DNA point mutations in cancer research.

Ondraskova K et al.

Analytical and Bioanalytical Chemistry, 2023

Inhibition of the Phosphatidylinositol-3 Kinase Pathway Using Bimiralisib in Loss-of-Function NOTCH1-Mutant Head and Neck Cancer.

Johnson FM et al.

The Oncologist, 2022

Binding of the B-Raf Inhibitors Dabrafenib and Vemurafenib to Human Serum Albumin: A Biophysical and Molecular Simulation Study.

Russi M et al.

Molecular Pharmaceutics, 2022

Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation.

Wang M et al.

Journal for Immunotherapy of Cancer, 2022

C677T and A1298C MTHFR gene polymorphisms and response to fluoropyrimidine-based chemotherapy in Mestizo patients with metastatic colorectal cancer.

Ramos-Esquivel A et al.

Pharmacogenetics and Genomics, 2021

Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Asselta R et al.

Thoracic Cancer, 2021

33704917 (PubMed )
Supplement: TCA-12-1271-s003.xls › Foglio1

High sensitivity sanger sequencing detection of BRAF mutations in metastatic melanoma FFPE tissue specimens.

Cheng LY et al.

Scientific Reports, 2021

33907234 (PubMed )
Supplement: 41598_2021_88391_MOESM1_ESM.pdf

Mutant-selective degradation by BRAF-targeting PROTACs.

Alabi S et al.

Nature Communications, 2021

Molecular profiling of the colon cancer in South-Eastern Romania: Results from the MERCUR study.

Popescu RC et al.

Medicine, 2021

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

Preliminary Study on the Relationship of BRAF Mutations with the Outcome of the First 131I Radiotherapy and Malignant Biological Characteristics in Papillary Thyroid Carcinoma.

Shangguan L et al.

International Journal of General Medicine, 2021

Genome scale analysis of pathogenic variants targetable for single base editing.

Lavrov AV et al.

Bmc Medical Genomics, 2020

32948190 (PubMed )
Supplement: 12920_2020_735_MOESM1_ESM.xlsx › mutations

Molecular and immunohistochemical analysis of BRAF gene in primary cutaneous melanoma: Discovery of novel mutations.

Fatnassi-Mersni G et al.

Journal of Cutaneous Pathology, 2020

Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Li J et al.

Journal of Translational Medicine, 2020

32738923 (PubMed )
Supplement: 12967_2020_2449_MOESM1_ESM.xlsx › Supplementary_Table_S2

Comparison of BRAF Mutation Screening Strategies in a Large Real-Life Series of Advanced Melanoma Patients.

Colombino M et al.

Journal of Clinical Medicine, 2020

BRAF Exon 15 Mutations in Papillary Carcinoma and Adjacent Thyroid Parenchyma: A Search for the Early Molecular Events Associated with Tumor Development.

Acquaviva G et al.

Cancers, 2020

Positive Correlation Between Somatic Mutations in RAS Gene and Colorectal Cancer in Telangana Population: Hospital-Based Study in a Cosmopolitan City.

Goud KI et al.

Applied Biochemistry and Biotechnology, 2020

Identification of Circulating Genomic and Metabolic Biomarkers in Intrahepatic Cholangiocarcinoma.

Winter H et al.

Cancers, 2019

31795195 (PubMed )
Supplement: cancers-11-01895-s001.zip › ICC_ctDNA_Cancers_Supplementary_Table_5._50_cancer_gene_panel_information.xlsx › cms_106003

Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.

Schneider B et al.

Pathology Oncology Research : Por, 2019

Acral Lentiginous Melanomas Harbour Intratumor Heterogeneity in BRAF Exon 15, With Mutations Distinct From V600E/V600K.

Fernandes M et al.

The American Journal of Dermatopathology, 2019

Molecular alterations and PD-L1 expression in non-ampullary duodenal adenocarcinoma: Associations among clinicopathological, immunophenotypic and molecular features.

Watari J et al.

Scientific Reports, 2019

Distinct Molecular Profiles and Immunotherapy Treatment Outcomes of V600E and V600K BRAF-Mutant Melanoma.

Pires da Silva I et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2019

Targeted mutation detection in breast cancer using MammaSeq™.

Smith NG et al.

Breast Cancer Research : Bcr, 2019

30736836 (PubMed )
Supplement: 13058_2019_1102_MOESM7_ESM.xlsx › Solid_Tumors

BRAF Mutation Status in Primary, Recurrent, and Metastatic Malignant Melanoma and Its Relation to Histopathological Parameters.

Spathis A et al.

Dermatology Practical & Conceptual, 2019

Competitive evolution of NSCLC tumor clones and the drug resistance mechanism of first-generation EGFR-TKIs in Chinese NSCLC patients.

Deng Q et al.

Heliyon, 2018

30603682 (PubMed )
Supplement: mmc2.xlsx › Raw_reads_info

Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.

Kim YS et al.

Bmc Urology, 2018

30064409 (PubMed )
Supplement: 12894_2018_380_MOESM1_ESM.xlsx › Supplementary_Table_1

DNA terminal structure-mediated enzymatic reaction for ultra-sensitive discrimination of single nucleotide variations in circulating cell-free DNA.

Wu T et al.

Nucleic Acids Research, 2018

Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract.

Lee JY et al.

Translational Oncology, 2018

29161613 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_1

Development of ultra-short PCR assay to reveal BRAF V600 mutation status in Thai colorectal cancer tissues.

Chat-Uthai N et al.

Plos One, 2018

BRAF Mutation Status Concordance Between Primary Cutaneous Melanomas and Corresponding Metastases: A Review of the Latest Evidence.

Godoy-Gijón E et al.

Actas Dermo-sifiliograficas, 2017

Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.

Richtig G et al.

The British Journal of Dermatology, 2017

Cell free DNA analysis by SiRe® next generation sequencing panel in non small cell lung cancer patients: focus on basal setting.

Pisapia P et al.

Journal of Thoracic Disease, 2017

Tall cell variant of papillary breast carcinoma: an additional case with review of the literature.

Pitino A et al.

Pathologica, 2017

The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas.

Ruiz R et al.

Plos Genetics, 2017

The landscape of BRAF transcript and protein variants in human cancer.

Marranci A et al.

Molecular Cancer, 2017

Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth.

Xia S et al.

Cell Metabolism, 2017

Activating BRAF Mutations Detected in Mixed Hürthle Cell Carcinoma and Multifocal Papillary Carcinoma of the Thyroid Gland: Report of an Unusual Case and Review of the Literature.

Sinno S et al.

International Journal of Surgical Pathology, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."