Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.T599A
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BRAF

NM_004333.6:p.T599A

Associated Papers

BRAF Non-V600 Mutations in Metastatic Colorectal Cancer.

Liu J et al.

Cancers, 2023

Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics.

Haefliger S et al.

Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology, 2023

36202073 (PubMed )
Supplement: pat-0090-0166-s01.pdf

Genomic Landscape, Clinical Features and Outcomes of Non-Small Cell Lung Cancer Patients Harboring BRAF Alterations of Distinct Functional Classes.

Di Federico A et al.

Cancers, 2022

35884534 (PubMed )
Supplement: cancers-14-03472-s001.zip › cancers-1806422-supplementary.pdf

Prevalence of class I-III BRAF mutations among 114,662 cancer patients in a large genomic database.

Owsley J et al.

Experimental Biology and Medicine (maywood, N.j.), 2021

BRAF Alteration in Central and Peripheral Nervous System Tumors.

Srinivasa K et al.

Frontiers in Oncology, 2020

Biochemical Characterization of Full-Length Oncogenic BRAFV600E together with Molecular Dynamics Simulations Provide Insight into the Activation and Inhibition Mechanisms of RAF Kinases.

Cope N et al.

Chembiochem : a European Journal of Chemical Biology, 2019

[Genetic testing of thyroid nodules using a gene panel developed on a new generation sequencing platform].

Kocsis-Deák B et al.

Orvosi Hetilap, 2019

Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.

Richtig G et al.

The British Journal of Dermatology, 2017

BRAF and MAP2K1 mutations in Langerhans cell histiocytosis: a study of 50 cases.

Alayed K et al.

Human Pathology, 2016

The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF.

Kiel C et al.

Elife, 2016

Clinical detection and categorization of uncommon and concomitant mutations involving BRAF.

Zheng G et al.

Bmc Cancer, 2015

Automated universal BRAF state detection within the activation segment in skin metastases by pyrosequencing-based assay U-BRAF(V600).

Skorokhod A et al.

Plos One, 2013

Lys63-linked polyubiquitination of BRAF at lysine 578 is required for BRAF-mediated signaling.

An L et al.

Scientific Reports, 2013

B-RAF mutant alleles associated with Langerhans cell histiocytosis, a granulomatous pediatric disease.

Satoh T et al.

Plos One, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."