Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.A598V
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BRAF

NM_004333.6:p.A598V

Associated Papers

Circulating tumor DNA profiling for non-invasive genomic analysis in Indian lung cancer patients: A real-world experience.

Jha P et al.

The Journal of Liquid Biopsy, 2025

40503459 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_S2

Actionable Mutations and Survival Rates in Non-Small Cell Lung Cancer.

Al-Qaisi TS et al.

World Journal of Oncology, 2025

Features and efficacy of triple-targeted therapy for patients with EGFR-mutant non-small-cell lung cancer with acquired BRAF alterations who are resistant to epidermal growth factor receptor tyrosine kinase inhibitors.

Li Y et al.

Esmo Open, 2024

Unveiling a rare BRAF mutation in minimally invasive follicular thyroid carcinoma: A case report.

Lee PS et al.

Medicine, 2024

Beyond tobacco: genomic disparities in lung cancer between smokers and never-smokers.

Garrido J et al.

Bmc Cancer, 2024

39097719 (PubMed )
Supplement: 12885_2024_12737_MOESM2_ESM.xlsx › Table_S1

Targeted next-generation sequencing of 491 lung cancers in clinical practice: Implications for future detection strategy and targeted therapy.

Liu XD et al.

Heliyon, 2024

38496837 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Diagnostic Utility of Next-Generation Sequencing in Circulating Free DNA and a Comparison With Matched Tissue in Gallbladder Carcinoma.

Mishra S et al.

Laboratory Investigation; a Journal of Technical Methods and Pathology, 2024

Follicular cell-derived thyroid carcinomas harboring novel genetic BRAFNON-V600E mutations: real-world data obtained using a multigene panel.

von Ammon JL et al.

Archives of Endocrinology and Metabolism, 2024

Unique Spectrum of Activating BRAF Alterations in Prostate Cancer.

Chehrazi-Raffle A et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023

37477913 (PubMed )
Supplement: ccr-23-1393_supplementary_data_1_suppds1.xlsx › Figure_2D

Hairy cell leukaemia with unusual BRAF mutations.

Maitre E et al.

Journal of Cellular and Molecular Medicine, 2023

Ongoing progress in BRAF-mutated non-small cell lung cancer.

Abdayem P et al.

Clinical Advances in Hematology & Oncology : H&o, 2022

Targeted Next-Generation Sequencing-Based Multiple Gene Mutation Profiling of Patients with Rectal Adenocarcinoma Receiving or Not Receiving Neoadjuvant Chemoradiotherapy.

Chang YK et al.

International Journal of Molecular Sciences, 2022

36142267 (PubMed )
Supplement: ijms-23-10353-s001.zip › ijms-1910530-supplementary.pdf

Genomic Landscape, Clinical Features and Outcomes of Non-Small Cell Lung Cancer Patients Harboring BRAF Alterations of Distinct Functional Classes.

Di Federico A et al.

Cancers, 2022

35884534 (PubMed )
Supplement: cancers-14-03472-s001.zip › cancers-1806422-supplementary.pdf

Targeting BRAF-mutant non-small cell lung cancer: Current status and future directions.

Riudavets M et al.

Lung Cancer (amsterdam, Netherlands), 2022

Somatic targeted mutation profiling of colorectal cancer precursor lesions.

Dos Santos W et al.

Bmc Medical Genomics, 2022

35761395 (PubMed )
Supplement: 12920_2022_1294_MOESM5_ESM.xlsx › Table_S2

Targeted Therapy for Melanomas Without BRAF V600 Mutations.

Menzer C et al.

Current Treatment Options in Oncology, 2022

High frequency of BRAF mutations in primary mucinous ovarian carcinoma of Taiwanese patients.

Chao WR et al.

Taiwanese Journal of Obstetrics & Gynecology, 2021

Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Asselta R et al.

Thoracic Cancer, 2021

33704917 (PubMed )
Supplement: TCA-12-1271-s003.xls › Foglio1

High sensitivity sanger sequencing detection of BRAF mutations in metastatic melanoma FFPE tissue specimens.

Cheng LY et al.

Scientific Reports, 2021

33907234 (PubMed )
Supplement: 41598_2021_88391_MOESM1_ESM.pdf

Distinct Somatic Alteration Features Identified by Gene Panel Sequencing in Korean Triple-Negative Breast Cancer with High Ki67 Expression.

Sun WY et al.

Diagnostics (basel, Switzerland), 2021

33804295 (PubMed )
Supplement: diagnostics-11-00416-s001.pdf

A Narrative Review of Genetic Alterations in Primary Thyroid Epithelial Cancer.

Romei C et al.

International Journal of Molecular Sciences, 2021

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

KANK1-NTRK3 fusions define a subset of BRAF mutation negative renal metanephric adenomas.

Catic A et al.

Bmc Medical Genetics, 2020

Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Li J et al.

Journal of Translational Medicine, 2020

32738923 (PubMed )
Supplement: 12967_2020_2449_MOESM2_ESM.xlsx › Supplementary_Table_S1

Development and Analytical Validation of an Expanded Mutation Detection Panel for Next-Generation Sequencing of Thyroid Nodule Aspirates.

Ablordeppey KK et al.

The Journal of Molecular Diagnostics : Jmd, 2020

Clonal selection confers distinct evolutionary trajectories in BRAF-driven cancers.

Gopal P et al.

Nature Communications, 2019

31723142 (PubMed )
Supplement: 41467_2019_13161_MOESM5_ESM.xlsx › Primers_or_Source_Vectors_

High Proportion of Potential Candidates for Immunotherapy in a Chilean Cohort of Gastric Cancer Patients: Results of the FORCE1 Study.

Cordova-Delgado M et al.

Cancers, 2019

31480291 (PubMed )
Supplement: cancers-11-01275-s001.zip › Supplementary_data_file_1.xlsx › DNA

The utility of combined mutation analysis and microRNA classification in reclassifying cancer risk of cytologically indeterminate thyroid nodules.

Banizs AB et al.

Diagnostic Cytopathology, 2019

Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Brown AL et al.

Plos Computational Biology, 2019

31034466 (PubMed )
Supplement: pcbi.1006981.s010.xlsx › final_benchmark

Targeting oncogenic Raf protein-serine/threonine kinases in human cancers.

Roskoski R

Pharmacological Research, 2018

Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations.

Dankner M et al.

Oncogene, 2018

Hobnail Variant of Papillary Thyroid Carcinoma: a Literature Review.

Ambrosi F et al.

Endocrine Pathology, 2017

Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.

Richtig G et al.

The British Journal of Dermatology, 2017

Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits.

Ma W et al.

Molecular Diagnosis & Therapy, 2017

Mutations in BRAF codons 594 and 596 predict good prognosis in melanoma.

Wu X et al.

Oncology Letters, 2017

Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis.

Emelyanova M et al.

Oncotarget, 2017

Somatic mutation profiling of hobnail variant of papillary thyroid carcinoma.

Morandi L et al.

Endocrine-related Cancer, 2017

Application of molecular biology of differentiated thyroid cancer for clinical prognostication.

Marotta V et al.

Endocrine-related Cancer, 2016

Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.

Kovaleva V et al.

Molecular Cancer, 2016

27756406 (PubMed )
Supplement: 12943_2016_549_MOESM2_ESM.xlsx › Kovaleva_SuppTableS4_BMC_MolCan

Circumscribed sebaceous neoplasms: a morphological, immunohistochemical and molecular analysis.

Harvey NT et al.

Pathology, 2016

The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes.

Pagan M et al.

Bmc Bioinformatics, 2016

26818556 (PubMed )
Supplement: 12859_2015_849_MOESM3_ESM.pdf

The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF.

Kiel C et al.

Elife, 2016

26744778 (PubMed )
Supplement: elife-12814-supp1.xlsx › input_random_forest

Clinical detection and categorization of uncommon and concomitant mutations involving BRAF.

Zheng G et al.

Bmc Cancer, 2015

BRAF and NRAS mutations are heterogeneous and not mutually exclusive in nodular melanoma.

Chiappetta C et al.

Applied Immunohistochemistry & Molecular Morphology : Aimm, 2015

Comprehensive Molecular Analysis of NSCLC; Clinicopathological Associations.

Chatziandreou I et al.

Plos One, 2015

Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Martelotto LG et al.

Genome Biology, 2014

25348012 (PubMed )
Supplement: 13059_2014_484_MOESM2_ESM.xlsx › Additional_file_2

BRAF pyrosequencing analysis aided by a lookup table.

Olson MT et al.

American Journal of Clinical Pathology, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."