Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.G596S
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BRAF

NM_004333.6:p.G596S

Associated Papers

Clinicopathological and molecular characterization of KRAS wild-type pancreatic ductal adenocarcinomas reveals precursor lesions with oncogenic mutations and fusions in RAS pathway genes.

Toriyama K et al.

The Journal of Pathology, 2025

40317966 (PubMed )
Supplement: PATH-266-337-s002.zip › path6432-sup-0003-TableS3.xlsx › Table_S3.1

Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma.

Dolgalev I et al.

Nature Communications, 2023

37938580 (PubMed )
Supplement: 41467_2023_42327_MOESM7_ESM.xlsx › snvs

Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.

Sakthikumar S et al.

Veterinary and Comparative Oncology, 2023

37248814 (PubMed )
Supplement: supplement_1.xlsx › Supp._Table_5

Molecular Divergence upon EGFR-TKI Resistance Could Be Dependent on the Exon Location of the Original EGFR-Sensitizing Mutation.

Serna-Blasco R et al.

Cancers, 2022

36139605 (PubMed )
Supplement: cancers-14-04446-s001.zip › Supplemental_data_S4.xlsx › variants_datasheet

Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

Chevrier S et al.

International Journal of Molecular Medicine, 2022

35244186 (PubMed )
Supplement: Supplementary_Data2.xlsx › Feuil1

Spectrum of BRAF Aberrations and Its Potential Clinical Implications: Insights From Integrative Pan-Cancer Analysis.

Yi Q et al.

Frontiers in Bioengineering and Biotechnology, 2022

35910024 (PubMed )
Supplement: Table2.XLSX › table

Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Yin XQ et al.

Frontiers in Oncology, 2022

35936718 (PubMed )
Supplement: Table_4.xlsx › MAF_infomation

Cetuximab plus irinotecan administered biweekly with reduced infusion time to heavily pretreated patients with metastatic colorectal cancer and related RAS and BRAF mutation status.

Jensen BV et al.

International Journal of Cancer, 2021

Spatially interacting phosphorylation sites and mutations in cancer.

Huang KL et al.

Nature Communications, 2021

33875650 (PubMed )
Supplement: 41467_2021_22481_MOESM4_ESM.xlsx › TableS5.ActMutationClusters

Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer.

Chin YM et al.

Cancer Science, 2021

33075187 (PubMed )
Supplement: CAS-112-454-s002.xlsx › Table_S11

Identification of pathogenic missense mutations using protein stability predictors.

Gerasimavicius L et al.

Scientific Reports, 2020

32958805 (PubMed )
Supplement: 41598_2020_72404_MOESM2_ESM.xlsx › ClinVar

TGPred: a tumor gene prediction webserver for analyzing structural and functional impacts of variants.

Liu J et al.

Journal of Molecular Cell Biology, 2020

32246141 (PubMed )
Supplement: supplementary_material_mjaa007.pdf

BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma.

Boyle EM et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2020

Targeted mutation detection in breast cancer using MammaSeq™.

Smith NG et al.

Breast Cancer Research : Bcr, 2019

30736836 (PubMed )
Supplement: 13058_2019_1102_MOESM7_ESM.xlsx › Solid_Tumors

Non-hodgkin lymphoma in a patient with cardiofaciocutaneous syndrome.

Ohtake A et al.

Journal of Pediatric Hematology/oncology, 2011

Comparison of allelic discrimination by dHPLC, HRM, and TaqMan in the detection of BRAF mutation V600E.

Carbonell P et al.

The Journal of Molecular Diagnostics : Jmd, 2011

Lack of cytoplasmic ERK activation is an independent adverse prognostic factor in primary cutaneous melanoma.

Jovanovic B et al.

The Journal of Investigative Dermatology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."