Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.N581T
Back to variants list

BRAF

NM_004333.6:p.N581T

Associated Papers

Clinical Molecular Testing for Clonal Relatedness of Second Melanoma Tumors: A Real-World Appraisal.

Plotzke JM et al.

Archives of Pathology & Laboratory Medicine, 2025

Invasive urothelial carcinoma with chordoid and myxoid features shows increased RAS/RAF pathway alterations.

Chan E et al.

Human Pathology, 2025

Genomic Landscapes of Early-Onset Versus Average-Onset Colorectal Cancer Populations.

Storandt MH et al.

Cancers, 2025

40075683 (PubMed )
Supplement: cancers-17-00836-s001.zip › cancers-3446894-supplementary.pdf

BRAF V600E and Non-V600E Mutations in RAS Wild-Type Metastatic Colorectal Cancer: Prognostic and Therapeutic Insights from a Nationwide, Multicenter, Observational Study (J-BROS).

Taniguchi H et al.

Cancers, 2025

MET amplification correlates with poor prognosis and immunotherapy response as a subtype of melanoma: a multicenter retrospective study.

Cai X et al.

Bmc Cancer, 2024

39528978 (PubMed )
Supplement: 12885_2024_13163_MOESM1_ESM.xlsx › SNVs

Targeting Non-V600 Mutations in BRAF: A Single Institution Retrospective Analysis and Review of the Literature.

Chaudhary HA et al.

Drugs in R&d, 2024

Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients.

Halik A et al.

Journal of Hematology & Oncology, 2024

39160538 (PubMed )
Supplement: 13045_2024_1590_MOESM1_ESM.xlsx › Suppl._Dataset_4_TS_SNV

Genomic landscape and tumor mutational features of resected preinvasive to invasive lung adenocarcinoma.

Lin Y et al.

Frontiers in Oncology, 2024

38803537 (PubMed )
Supplement: Table_1.xlsx › Table_S3

Comparative Genomic Analysis and Clinical Outcomes of BRAF-mutated Advanced Biliary Tract Cancers.

Tang TY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023

Unique Spectrum of Activating BRAF Alterations in Prostate Cancer.

Chehrazi-Raffle A et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023

37477913 (PubMed )
Supplement: ccr-23-1393_supplementary_data_1_suppds1.xlsx › Figure_2D

Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.

Sakthikumar S et al.

Veterinary and Comparative Oncology, 2023

37248814 (PubMed )
Supplement: supplement_1.xlsx › Supp._Table_5

Clinical, Mutational, and Transcriptomic Characteristics in Elderly Korean Individuals With Clonal Hematopoiesis Driver Mutations.

Moon I et al.

Annals of Laboratory Medicine, 2023

36281508 (PubMed )
Supplement: alm-43-2-145-supple2.pdf

Clinical and molecular characteristics of kinase domain duplications across diverse cancer types in the Chinese population.

Lai X et al.

Cancer Medicine, 2023

36325957 (PubMed )
Supplement: CAM4-12-6009-s003.xlsx › Table_S2

Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma.

Ansari-Pour N et al.

Blood, 2023

36223594 (PubMed )
Supplement: BLOOD_BLD-2022-017010-mmc2.xlsx › Supplementary_Table_S2

Multidrug resistance in the standardized treatment of colon cancer harboring a rare fibrosarcoma B-type (BRAF) p.N581I mutation: a case report.

Wang X et al.

Frontiers in Oncology, 2023

Distinct mutational features across preinvasive and invasive subtypes identified through comprehensive profiling of surgically resected lung adenocarcinoma.

Xiang C et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2022

35641658 (PubMed )
Supplement: 41379_2022_1076_MOESM1_ESM.pdf

Genomic Landscape, Clinical Features and Outcomes of Non-Small Cell Lung Cancer Patients Harboring BRAF Alterations of Distinct Functional Classes.

Di Federico A et al.

Cancers, 2022

35884534 (PubMed )
Supplement: cancers-14-03472-s001.zip › cancers-1806422-supplementary.pdf

Detection of oncogenic and clinically actionable mutations in cancer genomes critically depends on variant calling tools.

Garcia-Prieto CA et al.

Bioinformatics (oxford, England), 2022

35512388 (PubMed )
Supplement: btac306_supplementary_data.zip › Supplementary_files.zip › Supplementary_files › Supplementary_file_7.xlsx › Sheet1

Clinical Application of Comprehensive Genomic Profiling Tests for Diffuse Gliomas.

Omura T et al.

Cancers, 2022

35626060 (PubMed )
Supplement: cancers-14-02454-s001.zip › cancers-1674301-SI.xlsx › gene_aberrations

Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Sobahy TM et al.

Bmc Medical Genomics, 2022

35468810 (PubMed )
Supplement: 12920_2022_1235_MOESM3_ESM.xlsx › OncoKB_unspecified-alterations.

Spectrum of BRAF Aberrations and Its Potential Clinical Implications: Insights From Integrative Pan-Cancer Analysis.

Yi Q et al.

Frontiers in Bioengineering and Biotechnology, 2022

35910024 (PubMed )
Supplement: Table2.XLSX › table

Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden.

Georgoulias G et al.

Frontiers in Immunology, 2022

36389735 (PubMed )
Supplement: Table_7.xlsx › BRAF

MicroRNA Isoforms Contribution to Melanoma Pathogenesis.

Broseghini E et al.

Non-coding Rna, 2021

34698264 (PubMed )
Supplement: ncrna-07-00063-s001.zip › Supplementary_table_7.xlsx › finale

Histiocytic and Dendritic Cell Sarcomas of Hematopoietic Origin Share Targetable Genomic Alterations Distinct from Follicular Dendritic Cell Sarcoma.

Massoth LR et al.

The Oncologist, 2021

33904632 (PubMed )
Supplement: ONCO-26-e1263-s001.xlsx › Variants

BRN2 is a non-canonical melanoma tumor-suppressor.

Hamm M et al.

Nature Communications, 2021

34140478 (PubMed )
Supplement: 41467_2021_23973_MOESM1_ESM.pdf

Sensitivity, specificity, and accuracy of a liquid biopsy approach utilizing molecular amplification pools.

Garcia J et al.

Scientific Reports, 2021

34031447 (PubMed )
Supplement: 41598_2021_89592_MOESM1_ESM.xlsx › Supplementary_Table_S2

Genetic Heterogeneity of MET-Aberrant NSCLC and Its Impact on the Outcome of Immunotherapy.

Kron A et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2021

Identification of pathogenic missense mutations using protein stability predictors.

Gerasimavicius L et al.

Scientific Reports, 2020

32958805 (PubMed )
Supplement: 41598_2020_72404_MOESM2_ESM.xlsx › ClinVar

Molecular and immunohistochemical analysis of BRAF gene in primary cutaneous melanoma: Discovery of novel mutations.

Fatnassi-Mersni G et al.

Journal of Cutaneous Pathology, 2020

TGPred: a tumor gene prediction webserver for analyzing structural and functional impacts of variants.

Liu J et al.

Journal of Molecular Cell Biology, 2020

32246141 (PubMed )
Supplement: supplementary_material_mjaa007.pdf

Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan.

Taniguchi H et al.

Translational Oncology, 2020

Clinical mutational profiling and categorization of BRAF mutations in melanomas using next generation sequencing.

Lokhandwala PM et al.

Bmc Cancer, 2019

Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.

Richtig G et al.

The British Journal of Dermatology, 2017

Molecular profiling of intrahepatic and extrahepatic cholangiocarcinoma using next generation sequencing.

Putra J et al.

Experimental and Molecular Pathology, 2015

Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types.

Lebofsky R et al.

Molecular Oncology, 2015

A meta-analysis of somatic mutations from next generation sequencing of 241 melanomas: a road map for the study of genes with potential clinical relevance.

Xia J et al.

Molecular Cancer Therapeutics, 2014

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

Krauthammer M et al.

Nature Genetics, 2012

22842228 (PubMed )
Supplement: NIHMS390374-supplement-1.pdf
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."