Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.L514V
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BRAF

NM_004333.6:p.L514V

Associated Papers

Combining Molecular Dynamics and Machine Learning to Predict Drug Resistance Causing Variants of BRAF in Colorectal Cancer.

Xie L et al.

Molecules (basel, Switzerland), 2025

Management of asynchronous multifocal adult glioblastoma with loss of BRAFV600E -mutant clonality: a case report.

Haile H et al.

Acta Neuropathologica Communications, 2025

BRAF - a tumour-agnostic drug target with lineage-specific dependencies.

Hanrahan AJ et al.

Nature Reviews. Clinical Oncology, 2024

BRAF Mutations in CNS Tumors-Prognostic Markers and Therapeutic Targets.

Muniz TP et al.

Cns Drugs, 2023

Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAFV600E-Mutant Human Glioma.

Schreck KC et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2021

Targeted Therapy for BRAF Mutant Brain Tumors.

Rayi A et al.

Current Treatment Options in Oncology, 2021

Melanoma: Double BRAF mutation, double chance to treat?

Proietti I et al.

Dermatologic Therapy, 2020

BRAF mutation and its inhibitors in sarcoma treatment.

Liu H et al.

Cancer Medicine, 2020

CRISPR Screens Identify Essential Cell Growth Mediators in BRAF Inhibitor-resistant Melanoma.

Li Z et al.

Genomics, Proteomics & Bioinformatics, 2020

Challenges of targeting BRAF V600E mutations in adult primary brain tumor patients: a report of two cases.

Smith-Cohn M et al.

Cns Oncology, 2019

BRAF Mutations and the Utility of RAF and MEK Inhibitors in Primary Brain Tumors.

Schreck KC et al.

Cancers, 2019

A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAFV600E-Mutant Brain Tumor.

Wang J et al.

Cancer Discovery, 2018

BRAF Dimerization: An Underlying Resistance Mechanism in Low-Grade Pediatric Gliomas.

Romano G et al.

Cancer Discovery, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."