Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.G474R
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BRAF

NM_004333.6:p.G474R

Associated Papers

Unveiling a rare BRAF mutation in minimally invasive follicular thyroid carcinoma: A case report.

Lee PS et al.

Medicine, 2024

Integrated molecular and clinical analysis of BRAF-mutant glioma in adults.

Schreck KC et al.

Npj Precision Oncology, 2023

Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Brown AL et al.

Plos Computational Biology, 2019

31034466 (PubMed )
Supplement: pcbi.1006981.s010.xlsx › final_benchmark

Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Martelotto LG et al.

Genome Biology, 2014

25348012 (PubMed )
Supplement: 13059_2014_484_MOESM2_ESM.xlsx › Additional_file_2

Functional characterization of the novel BRAF complex mutation, BRAF(V600delinsYM) , identified in papillary thyroid carcinoma.

Matsuse M et al.

International Journal of Cancer, 2013

Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma.

Santarpia L et al.

Cancer, 2010

Insights into the molecular function of the inactivating mutations of B-Raf involving the DFG motif.

Moretti S et al.

Biochimica Et Biophysica Acta, 2009

Functional characterization of the novel T599I-VKSRdel BRAF mutation in a follicular variant papillary thyroid carcinoma.

De Falco V et al.

The Journal of Clinical Endocrinology and Metabolism, 2008

Clinical prognosis in BRAF-mutated PTC.

Puxeddu E et al.

Arquivos Brasileiros De Endocrinologia E Metabologia, 2007

Significance of BRAF mutations in papillary thyroid carcinoma: prognostic and therapeutic implications.

Groussin L et al.

Nature Clinical Practice. Endocrinology & Metabolism, 2006

PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma.

Castro P et al.

The Journal of Clinical Endocrinology and Metabolism, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."