Associated Papers
Biochemical Characterization of Full-Length Oncogenic BRAFV600E together with Molecular Dynamics Simulations Provide Insight into the Activation and Inhibition Mechanisms of RAF Kinases.
Cope N et al.
Chembiochem : a European Journal of Chemical Biology, 2019
RAF inhibitors activate the MAPK pathway by relieving inhibitory autophosphorylation.
Holderfield M et al.
Cancer Cell, 2013
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