Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.G464A
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BRAF

NM_004333.6:p.G464A

Associated Papers

Braf-mutant metastatic non-small-cell lung cancer: Real world data from the Italian biomarker atlas database.

Sini C et al.

European Journal of Cancer (oxford, England : 1990), 2026

Molecular genetic analysis of colorectal carcinoma with an aggressive extraintestinal immunohistochemical phenotype.

Hrudka J et al.

Scientific Reports, 2024

39333321 (PubMed )
Supplement: 41598_2024_72687_MOESM2_ESM.xlsx › 1

Pathways and targeting avenues of BRAF in non-small cell lung cancer.

Imyanitov EN et al.

Expert Opinion on Therapeutic Targets, 2024

MEK Inhibition for RASopathy-Associated Hypertrophic Cardiomyopathy: Clinical Application of a Basic Concept.

Chaput D et al.

The Canadian Journal of Cardiology, 2024

The Clinical, Genomic, and Transcriptomic Landscape of BRAF Mutant Cancers.

Kazandjian S et al.

Cancers, 2024

38275886 (PubMed )
Supplement: cancers-16-00445-s001.zip › Supplementary_Tables_S1-S18.xlsx › S1_Incidence_BRAF_Alterations

BRAF Non-V600 Mutations in Metastatic Colorectal Cancer.

Liu J et al.

Cancers, 2023

Multidrug resistance in the standardized treatment of colon cancer harboring a rare fibrosarcoma B-type (BRAF) p.N581I mutation: a case report.

Wang X et al.

Frontiers in Oncology, 2023

Distinct mutational features across preinvasive and invasive subtypes identified through comprehensive profiling of surgically resected lung adenocarcinoma.

Xiang C et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2022

35641658 (PubMed )
Supplement: 41379_2022_1076_MOESM1_ESM.pdf

Genomic Landscape, Clinical Features and Outcomes of Non-Small Cell Lung Cancer Patients Harboring BRAF Alterations of Distinct Functional Classes.

Di Federico A et al.

Cancers, 2022

35884534 (PubMed )
Supplement: cancers-14-03472-s001.zip › cancers-1806422-supplementary.pdf

Characteristics of and Treatment Strategies for Advanced EGFR-Mutant NSCLC With Concomitant BRAF Variations.

Wei XW et al.

Jto Clinical and Research Reports, 2022

35789792 (PubMed )
Supplement: mmc3.xlsx › Supplementary_Table_1

RASopathy Cohort of Patients Enrolled in a Brazilian Reference Center for Rare Diseases: A Novel Familial LZTR1 Variant and Recurrent Mutations.

Chaves Rabelo N et al.

The Application of Clinical Genetics, 2022

Modeling Clinical Responses to Targeted Therapies by Patient-Derived Organoids of Advanced Lung Adenocarcinoma.

Kim SY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2021

ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to chemotherapy in lung cancer.

Moreno T et al.

Oncogene, 2021

33742126 (PubMed )
Supplement: EMS118565-supplement-Suppl__Table_3.xlsx › Original_screenig

Prevalence of class I-III BRAF mutations among 114,662 cancer patients in a large genomic database.

Owsley J et al.

Experimental Biology and Medicine (maywood, N.j.), 2021

PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas.

Hill KS et al.

Molecular Cancer Research : Mcr, 2019

30355677 (PubMed )
Supplement: 15417786mcr180777-sup-205842_2_supp_5055633_pfqw03.pdf

BRAF internal deletions and resistance to BRAF/MEK inhibitor therapy.

Johnson DB et al.

Pigment Cell & Melanoma Research, 2018

BRAF in Lung Cancers: Analysis of Patient Cases Reveals Recurrent BRAF Mutations, Fusions, Kinase Duplications, and Concurrent Alterations.

Sheikine Y et al.

Jco Precision Oncology, 2018

Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material.

de Leng WW et al.

Plos One, 2016

26919633 (PubMed )
Supplement: pone.0149405.s010.xlsx › testset

Bioinformatics Approach for Prediction of Functional Coding/Noncoding Simple Polymorphisms (SNPs/Indels) in Human BRAF Gene.

Hassan MM et al.

Advances in Bioinformatics, 2016

Structure-functional prediction and analysis of cancer mutation effects in protein kinases.

Dixit A et al.

Computational and Mathematical Methods in Medicine, 2014

The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders.

Aoki Y et al.

Human Mutation, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."