Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.V459L
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BRAF

NM_004333.6:p.V459L

Associated Papers

Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies.

Bahar ME et al.

Signal Transduction and Targeted Therapy, 2023

BRAF mutations and concurrent alterations in patients with soft tissue sarcoma.

Kobayashi H et al.

Genes, Chromosomes & Cancer, 2023

BRAF Non-V600 Mutations in Metastatic Colorectal Cancer.

Liu J et al.

Cancers, 2023

Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Vranic S et al.

Acta Medica Academica, 2022

Ongoing progress in BRAF-mutated non-small cell lung cancer.

Abdayem P et al.

Clinical Advances in Hematology & Oncology : H&o, 2022

RAF-MEK-ERK pathway in cancer evolution and treatment.

Ullah R et al.

Seminars in Cancer Biology, 2022

BRAF and MEK Targeted Therapies in Pediatric Central Nervous System Tumors.

Talloa D et al.

Cancers, 2022

Genomic Landscape, Clinical Features and Outcomes of Non-Small Cell Lung Cancer Patients Harboring BRAF Alterations of Distinct Functional Classes.

Di Federico A et al.

Cancers, 2022

35884534 (PubMed )
Supplement: cancers-14-03472-s001.zip › cancers-1806422-supplementary.pdf

Targeting BRAF-mutant non-small cell lung cancer: Current status and future directions.

Riudavets M et al.

Lung Cancer (amsterdam, Netherlands), 2022

Melanoma with genetic alterations beyond the BRAFV600 mutation: management and new insights.

Awada G et al.

Current Opinion in Oncology, 2022

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

BRAF: A Two-Faced Janus.

Pisapia P et al.

Cells, 2020

Emerging BRAF Mutations in Cancer Progression and Their Possible Effects on Transcriptional Networks.

Śmiech M et al.

Genes, 2020

Association between BRAF mutant classification and the efficacy of pemetrexed-based chemotherapy in Chinese advanced non-small cell lung cancer patients: a multicenter retrospective study.

Lei L et al.

Translational Cancer Research, 2020

Targeting Oncogenic BRAF: Past, Present, and Future.

Zaman A et al.

Cancers, 2019

Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS.

Yao Z et al.

Nature, 2017

A Braf kinase-inactive mutant induces lung adenocarcinoma.

Nieto P et al.

Nature, 2017

BRAF mutation testing in clinical practice.

Ziai J et al.

Expert Review of Molecular Diagnostics, 2012

The energy landscape analysis of cancer mutations in protein kinases.

Dixit A et al.

Plos One, 2011

21998754 (PubMed )
Supplement: pone.0026071.s009.doc

Development and applications of a BRAF oligonucleotide microarray.

Kim IJ et al.

The Journal of Molecular Diagnostics : Jmd, 2007

BRAF mutation detection and identification by cycling temperature capillary electrophoresis.

Hinselwood DC et al.

Electrophoresis, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."