Varaico: Literature-Extracted Genetic Variants

Gene:BRAF
Variant:p.A12S
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BRAF

NM_004333.6:p.A12S

Associated Papers

Molecular Profiling of KRAS, NRAS, and BRAF in Colorectal Cancer: Insights From a Libyan Cohort.

Tawel HM et al.

Cureus, 2025

Dynamics of RAS Mutations in Liquid Biopsies in Metastatic Colorectal Cancer Patients-Case Series and Literature Review.

Popescu I et al.

Journal of Personalized Medicine, 2024

39064004 (PubMed )
Supplement: jpm-14-00750-s001.zip › jpm-3006960-supplementary.pdf

Colibactin mutational signatures in NTHL1 tumor syndrome and MUTYH associated polyposis patients.

Terlouw D et al.

Genes, Chromosomes & Cancer, 2024

Association of mutation profiles with metastasis in patients with non-small cell lung cancer.

Li Y et al.

Frontiers in Oncology, 2024

39464712 (PubMed )
Supplement: Table3.xlsx › LMG____

Mutation Analysis of KRAS and BRAF in Iranian Colorectal Cancer patients: A Novel Variant in Exon 15 of BRAF.

Hassani B et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2023

KRAS Mutation Status in Bulgarian Patients with Advanced and Metastatic Colorectal Cancer.

Radanova M et al.

International Journal of Molecular Sciences, 2023

High Wnt2 Expression Confers Poor Prognosis in Colorectal Cancer, and Represents a Novel Therapeutic Target in BRAF-Mutated Colorectal Cancer.

Liu H et al.

Medicina (kaunas, Lithuania), 2023

Genetics of brain arteriovenous malformations and cerebral cavernous malformations.

Hongo H et al.

Journal of Human Genetics, 2023

Electrochemical biosensors for analysis of DNA point mutations in cancer research.

Ondraskova K et al.

Analytical and Bioanalytical Chemistry, 2023

Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

Chevrier S et al.

International Journal of Molecular Medicine, 2022

35244186 (PubMed )
Supplement: Supplementary_Data2.xlsx › Feuil1

Discrimination of Single-Nucleotide Variants Based on an Allele-Specific Hybridization Chain Reaction and Smartphone Detection.

Lázaro A et al.

Acs Sensors, 2022

35188365 (PubMed )
Supplement: se1c02220_si_001.pdf

Papillary renal neoplasm with reverse polarity: A clinicopathological and molecular genetic characterization of 16 cases with expanding the morphologic spectrum and further support for a novel entity.

Shen M et al.

Frontiers in Oncology, 2022

Development and Validation of Targeted Gene Sequencing Panel Based Companion Diagnostic for Korean Patients with Solid Tumors.

Min BJ et al.

Cancers, 2021

Clinical Utility of Targeted Sequencing in Lung Cancer: Experience From an Autonomous Swedish Health Care Center.

Isaksson S et al.

Jto Clinical and Research Reports, 2020

Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer.

Duplaquet L et al.

Molecular Cancer Therapeutics, 2019

Rapid Somatic Mutation Testing in Colorectal Cancer by Use of a Fully Automated System and Single-Use Cartridge: A Comparison with Next-Generation Sequencing.

Al-Turkmani MR et al.

The Journal of Applied Laboratory Medicine, 2018

Prevalence of BRAF, NRAS and c-KIT mutations in Slovenian patients with advanced melanoma.

Moltara ME et al.

Radiology and Oncology, 2018

A KRAS wild type mutational status confers a survival advantage in pancreatic ductal adenocarcinoma.

Windon AL et al.

Journal of Gastrointestinal Oncology, 2018

"Squirrel" Primer-Based PCR Assay for Direct and Targeted Sanger Sequencing of Short Genomic Segments.

Ebili HO et al.

Journal of Biomolecular Techniques : Jbt, 2017

Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis.

Emelyanova M et al.

Oncotarget, 2017

28881731 (PubMed )
Supplement: oncotarget-08-52304-s002.xlsx › Sheet1

Prevalence and coexistence of KRAS, BRAF, PIK3CA, NRAS, TP53, and APC mutations in Indian colorectal cancer patients: Next-generation sequencing-based cohort study.

Jauhri M et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2017

Molecular genetic changes in benign colorectal tumors synchronous with microsatellite unstable carcinomas do not support a field defect.

Zauber P et al.

International Journal of Molecular Epidemiology and Genetics, 2017

[Correlation Research between Syndrome Elements of Chinese Medicine and KRAS, BRAF, NRAS Gene Mutations in Advanced Colorectal Cancer Patients].

Xu ZN et al.

Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine, 2016

Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases.

Løes IM et al.

International Journal of Cancer, 2016

26991344 (PubMed )
Supplement: IJC-139-647-s003.xls › Suppl_Tbl_2

Mutation Analysis of KRAS and BRAF Genes in Metastatic Colorectal Cancer: a First Large Scale Study from Iran.

Koochak A et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2016

Distribution of KRAS and BRAF Mutations in Metastatic Colorectal Cancers in Turkish Patients.

Gorukmez O et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2016

Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer.

Kopetz S et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2015

26460303 (PubMed )
Supplement: supp_33.34.4032_DS_2015.632497.pdf

Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics.

Magliacane G et al.

Oncotarget, 2015

RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers.

Boleij A et al.

Oncotarget, 2015

25944693 (PubMed )
Supplement: oncotarget-06-15681-s002.xlsx › Supplementary_table_1

A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer.

Kawazoe A et al.

Bmc Cancer, 2015

25886136 (PubMed )
Supplement: 12885_2015_1276_MOESM1_ESM.xlsx › Addtional_file_1

Non-invasive sensitive detection of KRAS and BRAF mutation in circulating tumor cells of colorectal cancer patients.

Mohamed Suhaimi NA et al.

Molecular Oncology, 2015

The molecular basis of rectal cancer.

Shiller M et al.

Clinics in Colon and Rectal Surgery, 2015

Germline CDKN2A mutations in Brazilian patients of hereditary cutaneous melanoma.

de Ávila AL et al.

Familial Cancer, 2014

Performance of amplicon-based next generation DNA sequencing for diagnostic gene mutation profiling in oncopathology.

Sie D et al.

Cellular Oncology (dordrecht, Netherlands), 2014

Detection of the BRAF V600E mutation in colon carcinoma: critical evaluation of the imunohistochemical approach.

Lasota J et al.

The American Journal of Surgical Pathology, 2014

Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review.

Imamura Y et al.

Molecular Cancer, 2014

Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications.

Kosmidou V et al.

Human Mutation, 2014

Next generation MUT-MAP, a high-sensitivity high-throughput microfluidics chip-based mutation analysis panel.

Schleifman EB et al.

Plos One, 2014

KRAS genotypic changes of circulating tumor cells during treatment of patients with metastatic colorectal cancer.

Kalikaki A et al.

Plos One, 2014

ARMS-PCR for detection of BRAF V600E hotspot mutation in comparison with Real-Time PCR-based techniques.

Machnicki MM et al.

Acta Biochimica Polonica, 2013

A new microarray substrate for ultra-sensitive genotyping of KRAS and BRAF gene variants in colorectal cancer.

Galbiati S et al.

Plos One, 2013

Rapid KRAS, EGFR, BRAF and PIK3CA mutation analysis of fine needle aspirates from non-small-cell lung cancer using allele-specific qPCR.

van Eijk R et al.

Plos One, 2011

21408138 (PubMed )
Supplement: pone.0017791.s001.xls › Supplementary_Table_S1

SNaPshot and StripAssay as valuable alternatives to direct sequencing for KRAS mutation detection in colon cancer routine diagnostics.

Fariña Sarasqueta A et al.

The Journal of Molecular Diagnostics : Jmd, 2011

High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue.

Tol J et al.

Journal of Cellular and Molecular Medicine, 2010

KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy.

Gaedcke J et al.

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology, 2010

Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants.

Hocker T et al.

Human Mutation, 2007

High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer.

Krypuy M et al.

Bmc Cancer, 2006

BRAF and KRAS mutations in stomach cancer.

Lee SH et al.

Oncogene, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."