Associated Papers
Molecular Mosaics: Unveiling Heterogeneity in Synchronous Colorectal Cancers.
Lee HG et al.
Cancer Research and Treatment, 2026
Recurrent ETV3::NCOA2 fusions and MAPK pathway mutations in indeterminate dendritic cell histiocytosis.
Kemps PG et al.
Blood Advances, 2025
Associations of KRAS Mutations and Clinical Characteristics of Colorectal Cancer Patients in Indonesia.
Rudiman R et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2024
Dynamics of RAS Mutations in Liquid Biopsies in Metastatic Colorectal Cancer Patients-Case Series and Literature Review.
Popescu I et al.
Journal of Personalized Medicine, 2024
Molecular Characterization of Advanced-Stage Melanomas in Clinical Practice Using a Laboratory-Developed Next-Generation Sequencing Panel.
Maloberti T et al.
Diagnostics (basel, Switzerland), 2024
Colibactin mutational signatures in NTHL1 tumor syndrome and MUTYH associated polyposis patients.
Terlouw D et al.
Genes, Chromosomes & Cancer, 2024
Correlation between KRAS Mutation and CTLA-4 mRNA Expression in Circulating Tumour Cells: Clinical Implications in Colorectal Cancer.
Aktar S et al.
Genes, 2023
High Wnt2 Expression Confers Poor Prognosis in Colorectal Cancer, and Represents a Novel Therapeutic Target in BRAF-Mutated Colorectal Cancer.
Liu H et al.
Medicina (kaunas, Lithuania), 2023
Utility of ctDNA Liquid Biopsies from Cancer Patients: An Institutional Study of 285 ctDNA Samples.
Gumà J et al.
Cancers, 2022
Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.
Chevrier S et al.
International Journal of Molecular Medicine, 2022
Development and Validation of Targeted Gene Sequencing Panel Based Companion Diagnostic for Korean Patients with Solid Tumors.
Min BJ et al.
Cancers, 2021
Age-Dependent De Novo Mutations During Spermatogenesis and Their Consequences.
Cioppi F et al.
Advances in Experimental Medicine and Biology, 2019
Integrative omics analyses broaden treatment targets in human cancer.
Sengupta S et al.
Genome Medicine, 2018
Multiple Hotspot Mutations Scanning by Single Droplet Digital PCR.
Decraene C et al.
Clinical Chemistry, 2018
Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis.
Emelyanova M et al.
Oncotarget, 2017
Costello Syndrome and Umbilical Ligament Rhabdomyosarcoma in Two Pediatric Patients: Case Reports and Review of the Literature.
Sánchez-Montenegro C et al.
Case Reports in Genetics, 2017
Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases.
Løes IM et al.
International Journal of Cancer, 2016
The lymphatic phenotype in Noonan and Cardiofaciocutaneous syndrome.
Joyce S et al.
European Journal of Human Genetics : Ejhg, 2016
Postzygotic BRAF p.Lys601Asn Mutation in Phacomatosis Pigmentokeratotica with Woolly Hair Nevus and Focal Cortical Dysplasia.
Kuentz P et al.
The Journal of Investigative Dermatology, 2016
Mutation Analysis of KRAS and BRAF Genes in Metastatic Colorectal Cancer: a First Large Scale Study from Iran.
Koochak A et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2016
Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer.
Kopetz S et al.
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2015
Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics.
Magliacane G et al.
Oncotarget, 2015
RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers.
Boleij A et al.
Oncotarget, 2015
A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer.
Kawazoe A et al.
Bmc Cancer, 2015
Non-invasive sensitive detection of KRAS and BRAF mutation in circulating tumor cells of colorectal cancer patients.
Mohamed Suhaimi NA et al.
Molecular Oncology, 2015
Preoperative RAS mutational analysis is of great value in predicting follicular variant of papillary thyroid carcinoma.
Hwang TS et al.
Biomed Research International, 2015
Detection of the BRAF V600E mutation in colon carcinoma: critical evaluation of the imunohistochemical approach.
Lasota J et al.
The American Journal of Surgical Pathology, 2014
Distinct profile of HIF1α, PTCH, EphB2, or DNA repair protein expression and BRAF mutation in colorectal serrated adenoma.
Morimoto T et al.
Journal of Gastroenterology and Hepatology, 2014
Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review.
Imamura Y et al.
Molecular Cancer, 2014
KRAS, NRAS and BRAF mutations in Greek and Romanian patients with colorectal cancer: a cohort study.
Negru S et al.
Bmj Open, 2014
Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications.
Kosmidou V et al.
Human Mutation, 2014
KRAS genotypic changes of circulating tumor cells during treatment of patients with metastatic colorectal cancer.
Kalikaki A et al.
Plos One, 2014
KRAS and BRAF mutations in 203 esophageal squamous cell carcinomas: pyrosequencing technology and literature review.
Shigaki H et al.
Annals of Surgical Oncology, 2013
A new microarray substrate for ultra-sensitive genotyping of KRAS and BRAF gene variants in colorectal cancer.
Galbiati S et al.
Plos One, 2013
Prognostic value of KRAS genotype in metastatic colorectal cancer (MCRC) patients treated with intensive triplet chemotherapy plus bevacizumab (FIr-B/FOx) according to extension of metastatic disease.
Bruera G et al.
Bmc Medicine, 2012
Phenotype and polyp landscape in serrated polyposis syndrome: a series of 100 patients from genetics clinics.
Rosty C et al.
The American Journal of Surgical Pathology, 2012
Costello syndrome: a Ras/mitogen activated protein kinase pathway syndrome (rasopathy) resulting from HRAS germline mutations.
Gripp KW et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2012
Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution.
Sylvester BE et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2012
Hyperplastic polyp of the duodenum: a report of 9 cases with immunohistochemical and molecular findings.
Rosty C et al.
Human Pathology, 2011
Increased sleep spindle activity in patients with Costello syndrome (HRAS gene mutation).
Della Marca G et al.
Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society, 2011
Rapid KRAS, EGFR, BRAF and PIK3CA mutation analysis of fine needle aspirates from non-small-cell lung cancer using allele-specific qPCR.
van Eijk R et al.
Plos One, 2011
SNaPshot and StripAssay as valuable alternatives to direct sequencing for KRAS mutation detection in colon cancer routine diagnostics.
Fariña Sarasqueta A et al.
The Journal of Molecular Diagnostics : Jmd, 2011
High sensitive mutation analysis on KRAS gene using LNA/DNA chimeras as PCR amplification blockers of wild-type alleles.
Huang Q et al.
Molecular and Cellular Probes, 2010
High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue.
Tol J et al.
Journal of Cellular and Molecular Medicine, 2010
Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome.
Schulz AL et al.
Clinical Genetics, 2008
Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants.
Hocker T et al.
Human Mutation, 2007
High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer.
Krypuy M et al.
Bmc Cancer, 2006
Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer.
Ogino S et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2005