Associated Papers
BRCA1 transports the DNA damage signal for CDDP-induced centrosome amplification through the centrosomal Aurora A.
Qi H et al.
Cancer Science, 2022
Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop.
Qi L et al.
Iscience, 2022
Molecular contribution of BRCA1 and BRCA2 to genome instability in breast cancer patients: review of radiosensitivity assays.
Sadeghi F et al.
Biological Procedures Online, 2020
Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection.
Parameswaran B et al.
Cell Cycle (georgetown, Tex.), 2015
DNA-PKcs activates the Chk2-Brca1 pathway during mitosis to ensure chromosomal stability.
Shang Z et al.
Oncogenesis, 2014
BRCA1 and γH2AX as independent prognostic markers in oral squamous cell carcinoma.
Oliveira-Costa JP et al.
Oncoscience, 2014
A high-throughput functional complementation assay for classification of BRCA1 missense variants.
Bouwman P et al.
Cancer Discovery, 2013
Mouse models of BRCA1 and their application to breast cancer research.
Dine J et al.
Cancer Metastasis Reviews, 2013
Links between genome integrity and BRCA1 tumor suppression.
Li ML et al.
Trends in Biochemical Sciences, 2012
BRCA1 and BRCA2: different roles in a common pathway of genome protection.
Roy R et al.
Nature Reviews. Cancer, 2011
DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation.
Wang H et al.
Cancer Research, 2010
The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells.
Stolz A et al.
Nature Cell Biology, 2010
A mitotic role for the DNA damage-responsive CHK2 kinase.
Sato K et al.
Nature Cell Biology, 2010
Expression of human BRCA1 variants in mouse ES cells allows functional analysis of BRCA1 mutations.
Chang S et al.
The Journal of Clinical Investigation, 2009
BRCA1 is regulated by Chk2 in response to spindle damage.
Chabalier-Taste C et al.
Biochimica Et Biophysica Acta, 2008
A PP1-binding motif present in BRCA1 plays a role in its DNA repair function.
Yu YM et al.
International Journal of Biological Sciences, 2008
Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining.
Wang HC et al.
Cancer Research, 2006
Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining.
Zhuang J et al.
Cancer Research, 2006
MDC1 interacts with Rad51 and facilitates homologous recombination.
Zhang J et al.
Nature Structural & Molecular Biology, 2005
The role of the BRCA1 tumor suppressor in DNA double-strand break repair.
Zhang J et al.
Molecular Cancer Research : Mcr, 2005
Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization.
Okada S et al.
The Journal of Biological Chemistry, 2003
Functions of BRCA1 and BRCA2 in the biological response to DNA damage.
Venkitaraman AR
Journal of Cell Science, 2001