Varaico: Literature-Extracted Genetic Variants

Gene:BRCA1
Variant:p.F869_G876delFs
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BRCA1

NM_007294.4:p.F869_G876delFs

Associated Papers

ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.

Yazinski SA et al.

Genes & Development, 2017

28242626 (PubMed )
Supplement: supp_gad.290957.116_Supplemental_Methods.pdf

Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas.

Norquist B et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2011

Secondary mutations of BRCA1/2 and drug resistance.

Dhillon KK et al.

Cancer Science, 2011

Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance.

Swisher EM et al.

Cancer Research, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."