Varaico: Literature-Extracted Genetic Variants

Gene:BRCA1
Variant:p.S768I
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BRCA1

NM_007294.4:p.S768I

Associated Papers

From Rarity to Reality: Osimertinib's Promising Horizon in Treating Uncommon EGFR Mutations in Non-Small Cell Lung Cancer.

Fukuda A et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2024

Case report: olaparib use in metastatic lung adenocarcinoma with BRCA2 pathogenic variant.

Soon Jian Hao J et al.

Cold Spring Harbor Molecular Case Studies, 2022

36577523 (PubMed )
Supplement: supp_mcs.a006223_Supplemental_Material.pdf

Comprehensive genomic profiling of Finnish lung adenocarcinoma cohort reveals high clinical actionability and SMARCA4 altered tumors with variable histology and poor prognosis.

Talvitie EM et al.

Neoplasia (new York, N.y.), 2022

Genomic Alteration Spectrum of Non-Small Cell Lung Cancer Patients in East-China Characterized by Tumor Tissue DNA and Cell-Free DNA.

Li J et al.

Oncotargets and Therapy, 2022

Comprehensive analyses of genomic features and mutational signatures in adenosquamous carcinoma of the lung.

Wang H et al.

Frontiers in Oncology, 2022

Liquid biopsy mutation panel for non-small cell lung cancer: analytical validation and clinical concordance.

Schwartzberg LS et al.

Npj Precision Oncology, 2020

Genomic Signature of Driver Genes Identified by Target Next-Generation Sequencing in Chinese Non-Small Cell Lung Cancer.

Wen S et al.

The Oncologist, 2019

Targeted Tissue and Cell-Free Tumor DNA Sequencing of Advanced Lung Squamous-Cell Carcinoma Reveals Clinically Significant Prevalence of Actionable Alterations.

Lam VK et al.

Clinical Lung Cancer, 2019

Mutations of the Epidermal Growth Factor Receptor Gene in Triple-Negative Breast Cancer.

Kim A et al.

Journal of Breast Cancer, 2017

Afatinib in Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations Pretreated With Reversible EGFR Inhibitors.

Heigener DF et al.

The Oncologist, 2015

Effectiveness of tyrosine kinase inhibitors on "uncommon" epidermal growth factor receptor mutations of unknown clinical significance in non-small cell lung cancer.

Wu JY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."