Varaico: Literature-Extracted Genetic Variants

Gene:BRCA1
Variant:p.N723delFs
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BRCA1

NM_007294.4:p.N723delFs

Associated Papers

Differential PARP inhibitor responses in BRCA1-deficient and resistant cells in competitive co-culture.

Soetomo SA et al.

Plos One, 2025

Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.

Meijer TG et al.

Cancers, 2024

A HUWE1 defect causes PARP inhibitor resistance by modulating the BRCA1-∆11q splice variant.

Pettitt SJ et al.

Oncogene, 2023

Discovering Synergistic Compounds with BYL-719 in PI3K Overactivated Basal-like PDXs.

Boyd DC et al.

Cancers, 2023

Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines.

Barnabas N et al.

International Journal of Breast Cancer, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."