Varaico: Literature-Extracted Genetic Variants

Gene:BRCA2
Variant:p.E49V
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BRCA2

NM_000059.4:p.E49V

Associated Papers

Fragmentomic-based algorithm to computationally predict tumor-somatic, germline, and clonal hematopoiesis variant origin in liquid biopsy.

Brown DW et al.

The Journal of Liquid Biopsy, 2025

40704056 (PubMed )
Supplement: mmc2.xlsx › Supp_Table_3

Mutational profiling using liquid biopsy to guide targeted therapy in patients with metastatic cancer.

Mazouji O et al.

Scientific Reports, 2025

40169620 (PubMed )
Supplement: 41598_2025_88094_MOESM2_ESM.xlsx › Feuil1

Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer.

Durinikova E et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2022

35881546 (PubMed )
Supplement: EMS151756-supplement-Table_S1.xlsx › Cell_lines

Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2.

Aljarf R et al.

Scientific Reports, 2022

35729312 (PubMed )
Supplement: 41598_2022_13508_MOESM2_ESM.xlsx › Sheet1

Clinical Application of Targeted Deep Sequencing in Metastatic Colorectal Cancer Patients: Actionable Genomic Alteration in K-MASTER Project.

Lee Y et al.

Cancer Research and Treatment, 2021

Germline variation in BRCA1/2 is highly ethnic-specific: Evidence from over 30,000 Chinese hereditary breast and ovarian cancer patients.

Bhaskaran SP et al.

International Journal of Cancer, 2019

30702160 (PubMed )
Supplement: IJC-145-962-s006.xlsx › Total_BRCA1___BRCA2

Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma.

Quaas A et al.

Bmc Gastroenterology, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."