Varaico: Literature-Extracted Genetic Variants

Gene:BRCA2
Variant:p.S193A
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BRCA2

NM_000059.4:p.S193A

Associated Papers

Intrinsic Disorder and Phosphorylation in BRCA2 Facilitate Tight Regulation of Multiple Conserved Binding Events.

Julien M et al.

Biomolecules, 2021

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1.

Ehlén Å et al.

Nature Communications, 2020

BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation.

Thirthagiri E et al.

Human Molecular Genetics, 2016

Molding BRCA2 function through its interacting partners.

Martinez JS et al.

Cell Cycle (georgetown, Tex.), 2015

BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC.

Takaoka M et al.

Cancer Research, 2014

M phase-specific phosphorylation of BRCA2 by Polo-like kinase 1 correlates with the dissociation of the BRCA2-P/CAF complex.

Lin HR et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."