Varaico: Literature-Extracted Genetic Variants

Gene:BRCA2
Variant:p.K585fs
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BRCA2

NM_000059.4:p.K585fs

Associated Papers

A phase Ib study of sapacitabine and olaparib in patients with BRCA1/2-mutated metastatic breast cancer.

Lynce F et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2025

41335237 (PubMed )
Supplement: ccr-25-0571_supplementary_data1_suppds1.docx

Allogeneic hematopoietic stem cell transplant outcomes in adults with inherited myeloid malignancies.

Saygin C et al.

Blood Advances, 2023

36001442 (PubMed )
Supplement: BLOODA_ADV-2022-008172-mmc1.pdf

New generation breast cancer cell lines developed from patient-derived xenografts.

Finlay-Schultz J et al.

Breast Cancer Research : Bcr, 2020

Consolidated BRCA1/2 Variant Interpretation by MH BRCA Correlates with Predicted PARP Inhibitor Efficacy Association by MH Guide.

Hirotsu Y et al.

International Journal of Molecular Sciences, 2020

32486089 (PubMed )
Supplement: ijms-21-03895-s001.zip › Supplemental_Table_2.xlsx › ARUP

Exome sequencing reveals a high prevalence of BRCA1 and BRCA2 founder variants in a diverse population-based biobank.

Abul-Husn NS et al.

Genome Medicine, 2019

31892343 (PubMed )
Supplement: 13073_2019_691_MOESM1_ESM.pdf

Pancreatic acinar cell carcinoma is associated with BRCA2 germline mutations: a case report and literature review.

Kryklyva V et al.

Cancer Biology & Therapy, 2019

Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic.

Foley SB et al.

Ebiomedicine, 2015

26023681 (PubMed )
Supplement: mmc1.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."