Varaico: Literature-Extracted Genetic Variants

Gene:BRCA2
Variant:p.K601E
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BRCA2

NM_000059.4:p.K601E

Associated Papers

Combining Molecular Dynamics and Machine Learning to Predict Drug Resistance Causing Variants of BRAF in Colorectal Cancer.

Xie L et al.

Molecules (basel, Switzerland), 2025

Targeting Non-V600 Mutations in BRAF: A Single Institution Retrospective Analysis and Review of the Literature.

Chaudhary HA et al.

Drugs in R&d, 2024

Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer.

Tewari AK et al.

Cell Reports, 2021

Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making.

Abida W et al.

Jco Precision Oncology, 2017

Somatic BRCA2 bi-allelic loss in the primary prostate cancer was associated to objective response to PARPi in a sporadic CRPC patient.

Romero-Laorden N et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2017

BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors.

Dahlman KB et al.

Cancer Discovery, 2012

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.

Nikolaev SI et al.

Nature Genetics, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."