Varaico: Literature-Extracted Genetic Variants

Gene:BRCA2
Variant:p.F1219L
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BRCA2

NM_000059.4:p.F1219L

Associated Papers

Germline variation in BRCA1/2 is highly ethnic-specific: Evidence from over 30,000 Chinese hereditary breast and ovarian cancer patients.

Bhaskaran SP et al.

International Journal of Cancer, 2019

30702160 (PubMed )
Supplement: IJC-145-962-s006.xlsx › BRCA2_ethnic_sources_

Analysis of Tissue and Circulating Tumor DNA by Next-Generation Sequencing of Hepatocellular Carcinoma: Implications for Targeted Therapeutics.

Ikeda S et al.

Molecular Cancer Therapeutics, 2018

Next-Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma.

Ikeda S et al.

The Oncologist, 2018

Cancer-associated mutations in BRC domains of BRCA2 affect homologous recombination induced by Rad51.

Tal A et al.

Journal of Molecular Biology, 2009

Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

Esashi F et al.

Nature Structural & Molecular Biology, 2007

Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer.

Lo T et al.

Dna Repair, 2003

Medical implications of DNA repair.

Yarosh DB

Cutis, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."