Associated Papers
BRCA2 and NF2-Mutated High-Grade Renal Cell Carcinoma: A Case Report and Literature Review.
Talafha MM et al.
International Journal of Surgical Pathology, 2026
A single BRCA2 BRC repeat supports viability while multiple repeats ensure resilience under stress.
Mishra AP et al.
Biorxiv : the Preprint Server for Biology, 2026
Positive and negative regulators of RAD51/DMC1 in homologous recombination and DNA replication.
Ito M et al.
Dna Repair, 2024
Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs.
Biswas K et al.
Cell Reports Methods, 2023
BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair.
Jimenez-Sainz J et al.
Elife, 2022
Breast cancer risks associated with missense variants in breast cancer susceptibility genes.
Dorling L et al.
Genome Medicine, 2022
Analysis of Sequence and Copy Number Variants in Canadian Patient Cohort With Familial Cancer Syndromes Using a Unique Next Generation Sequencing Based Approach.
Bhai P et al.
Frontiers in Genetics, 2021
Consolidated BRCA1/2 Variant Interpretation by MH BRCA Correlates with Predicted PARP Inhibitor Efficacy Association by MH Guide.
Hirotsu Y et al.
International Journal of Molecular Sciences, 2020
Classification of variants of uncertain significance in BRCA1 and BRCA2 using personal and family history of cancer from individuals in a large hereditary cancer multigene panel testing cohort.
Li H et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2020
REVEL and BayesDel outperform other in silico meta-predictors for clinical variant classification.
Tian Y et al.
Scientific Reports, 2019
Germline variation in BRCA1/2 is highly ethnic-specific: Evidence from over 30,000 Chinese hereditary breast and ovarian cancer patients.
Bhaskaran SP et al.
International Journal of Cancer, 2019
A Bayesian framework for efficient and accurate variant prediction.
Qian D et al.
Plos One, 2018
Cancer-associated mutations in BRC domains of BRCA2 affect homologous recombination induced by Rad51.
Tal A et al.
Journal of Molecular Biology, 2009
Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.
Esashi F et al.
Nature Structural & Molecular Biology, 2007
Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer.
Lo T et al.
Dna Repair, 2003
Insights into DNA recombination from the structure of a RAD51-BRCA2 complex.
Pellegrini L et al.
Nature, 2002
Clustering of variations and haplotype analysis in the highly variable region of exon 11 of BRCA1 in Chinese women with sporadic breast cancer.
Li Y et al.
Human Mutation, 2002