Varaico: Literature-Extracted Genetic Variants

Gene:BRCA2
Variant:p.T1980I
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BRCA2

NM_000059.4:p.T1980I

Associated Papers

BRCA2 and NF2-Mutated High-Grade Renal Cell Carcinoma: A Case Report and Literature Review.

Talafha MM et al.

International Journal of Surgical Pathology, 2026

Positive and negative regulators of RAD51/DMC1 in homologous recombination and DNA replication.

Ito M et al.

Dna Repair, 2024

Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs.

Biswas K et al.

Cell Reports Methods, 2023

The pathogenic role of the BRCA2 c.7847C>T (p.Ser2616Phe) variant in breast and ovarian cancer predisposition.

Yamazawa K et al.

Cancer Science, 2023

37067535 (PubMed )
Supplement: CAS-114-2993-s001.pdf

BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair.

Jimenez-Sainz J et al.

Elife, 2022

High-throughput functional evaluation of BRCA2 variants of unknown significance.

Ikegami M et al.

Nature Communications, 2020

32444794 (PubMed )
Supplement: 41467_2020_16141_MOESM6_ESM.xlsx › Information_of_244_variants

Genetics of breast cancer in African populations: a literature review.

Abbad A et al.

Global Health, Epidemiology and Genomics, 2018

Monoallelic characteristic-bearing heterozygous L1053X in BRCA2 gene among Sudanese women with breast cancer.

Elimam AA et al.

Bmc Medical Genetics, 2017

Contribution of BRCA1 and BRCA2 Germline Mutations to Early Algerian Breast Cancer.

Henouda S et al.

Disease Markers, 2016

Cancer-associated mutations in BRC domains of BRCA2 affect homologous recombination induced by Rad51.

Tal A et al.

Journal of Molecular Biology, 2009

Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

Esashi F et al.

Nature Structural & Molecular Biology, 2007

Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer.

Lo T et al.

Dna Repair, 2003

1–50 of 53 papers
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."