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Pathogenic variation in human DNA damage repair genes was originated from the evolutionary process of modern humans.
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Supplement: mmc1.xlsx › Sheet1
Pathogenic variants in human DNA damage repair genes mostly arose in recent human history.
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Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.
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Pathogenic variants in human DNA damage repair genes mostly arose after the latest human out-of-Africa migration.
He J et al.
Frontiers in Genetics, 2024
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Supplement: Table6.XLSX › Sheet1
Twenty Years of BRCA1 and BRCA2 Molecular Analysis at MMCI - Current Developments for the Classification of Variants.
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Klinicka Onkologie : Casopis Ceske a Slovenske Onkologicke Spolecnosti, 2019
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