Varaico: Literature-Extracted Genetic Variants

Gene:BRCA2
Variant:p.T2515fs
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BRCA2

NM_000059.4:p.T2515fs

Associated Papers

Ethnic-specificity, evolution origin and deleteriousness of Asian BRCA variation revealed by over 7500 BRCA variants derived from Asian population.

Qin Z et al.

International Journal of Cancer, 2023

36385461 (PubMed )
Supplement: IJC-152-1159-s010.xlsx › Asian_only

Human BRCA pathogenic variants were originated during recent human history.

Li J et al.

Life Science Alliance, 2022

35165121 (PubMed )
Supplement: LSA-2021-01263_TableS5.xlsx › BRCA2

Evaluation of 3 molecular-based assays for microsatellite instability detection in formalin-fixed tissues of patients with endometrial and colorectal cancers.

Gilson P et al.

Scientific Reports, 2020

33009475 (PubMed )
Supplement: 41598_2020_73421_MOESM1_ESM.pdf

Brca2 deficiency drives gastrointestinal tumor formation and is selectively inhibited by mitomycin C.

Chen X et al.

Cell Death & Disease, 2020

32980867 (PubMed )
Supplement: 41419_2020_3013_MOESM2_ESM.xlsx › BRCA2-mutant
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."