Associated Papers
A practice changing paper: biallelic inactivation of BRCA2 in Fanconi anaemia.
Prepelita D et al.
Bjc Reports, 2024
Therapeutic disruption of RAD52-ssDNA complexation via novel drug-like inhibitors.
Bhat DS et al.
Nar Cancer, 2023
A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death.
Scott DE et al.
Cell Chemical Biology, 2021
A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays.
Biswas K et al.
Npj Genomic Medicine, 2020
33293522 (PubMed )
Supplement: 41525_2020_158_MOESM1_ESM.pdf
Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells.
Sullivan-Reed K et al.
Cell Reports, 2018
29898385 (PubMed )
Supplement: NIHMS977847-supplement-1.pdf
The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.
Colombo M et al.
Human Mutation, 2018
Single-molecule localization microscopy reveals molecular transactions during RAD51 filament assembly at cellular DNA damage sites.
Haas KT et al.
Nucleic Acids Research, 2018
BRCA2 Regulates Transcription Elongation by RNA Polymerase II to Prevent R-Loop Accumulation.
Shivji MKK et al.
Cell Reports, 2018
A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability.
Tan SLW et al.
Cell, 2017
A novel role for non-ubiquitinated FANCD2 in response to hydroxyurea-induced DNA damage.
Chen X et al.
Oncogene, 2016
Cycling with BRCA2 from DNA repair to mitosis.
Lee H
Experimental Cell Research, 2014
Cellular characterization of cells from the Fanconi anemia complementation group, FA-D1/BRCA2.
Godthelp BC et al.
Mutation Research, 2006
Inherited FANCD1/BRCA2 exon 7 splice mutations associated with acute myeloid leukaemia in Fanconi anaemia D1 are not found in sporadic childhood leukaemia.
Barber LM et al.
British Journal of Haematology, 2005
A cross-linker-sensitive myeloid leukemia cell line from a 2-year-old boy with severe Fanconi anemia and biallelic FANCD1/BRCA2 mutations.
Meyer S et al.
Genes, Chromosomes & Cancer, 2005
Biallelic BRCA2 mutations are associated with multiple malignancies in childhood including familial Wilms tumour.
Reid S et al.
Journal of Medical Genetics, 2005
Shared genetic susceptibility to breast cancer, brain tumors, and Fanconi anemia.
Offit K et al.
Journal of the National Cancer Institute, 2003
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