Varaico: Literature-Extracted Genetic Variants

Gene:BRCA2
Variant:p.N2591insFs
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BRCA2

NM_000059.4:p.N2591insFs

Associated Papers

Mutational spectrum of DNA damage and mismatch repair genes in prostate cancer.

Bugoye FC et al.

Frontiers in Genetics, 2023

Implications of High Rates of Metastatic Prostate Cancer in BRCA2 Mutation Carriers.

Gleicher S et al.

The Prostate, 2016

The role of BRCA1 and BRCA2 in prostate cancer.

Li D et al.

Frontiers in Bioscience (landmark Edition), 2013

Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer.

Castro E et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2013

Characteristics and spectrum of BRCA1 and BRCA2 mutations in 3,922 Korean patients with breast and ovarian cancer.

Kim H et al.

Breast Cancer Research and Treatment, 2012

Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis.

Edwards SM et al.

British Journal of Cancer, 2010

Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype.

Mitra A et al.

British Journal of Cancer, 2008

BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives.

Lalloo F et al.

European Journal of Cancer (oxford, England : 1990), 2006

Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.

Edwards SM et al.

American Journal of Human Genetics, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."