Varaico: Literature-Extracted Genetic Variants

Gene:BRIP1
Variant:p.P47delFs
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BRIP1

NM_032043.3:p.P47delFs

Associated Papers

The prognostic and predictive value of homologous recombination deficiency status in patients with advanced stage epithelial ovarian carcinoma after first-line platinum-based chemotherapy.

Xu Y et al.

Frontiers in Oncology, 2024

Spatial and temporal intra-tumoral heterogeneity in advanced HGSOC: Implications for surgical and clinical outcomes.

Cunnea P et al.

Cell Reports. Medicine, 2023

37220750 (PubMed )
Supplement: mmc2.xlsx › Table_S1h

Inhibition of poly(ADP-ribose) polymerase induces synthetic lethality in BRIP1 deficient ovarian epithelial cells.

Ciccone MA et al.

Gynecologic Oncology, 2020

Delineation of the Germline and Somatic Mutation Interaction Landscape in Triple-Negative and Non-Triple-Negative Breast Cancer.

Wu J et al.

International Journal of Genomics, 2020

32724790 (PubMed )
Supplement: 2641370.f1.zip › mat.2641370.v2 › Table_SG.xlsx › Sheet2

Deconvolution of the Genomic and Epigenomic Interaction Landscape of Triple-Negative Breast Cancer.

Wu J et al.

Cancers, 2019

31683572 (PubMed )
Supplement: cancers-11-01692-s001.zip › cancers-602527-supplementary_publish › Table_S1.xlsx › Sheet2

Integrating Germline and Somatic Mutation Information for the Discovery of Biomarkers in Triple-Negative Breast Cancer.

Wu J et al.

International Journal of Environmental Research and Public Health, 2019

30909550 (PubMed )
Supplement: ijerph-16-01055-s001.zip › JIANDE-TNBC-TABLES-SA-GWAS_FV-SUPPL-_NEWCATALOGUE-14FEB2019.xlsx › Sheet1

Discovering moderate-risk breast cancer susceptibility genes.

Hollestelle A et al.

Current Opinion in Genetics & Development, 2010

Evaluation of variants in the CHEK2, BRIP1 and PALB2 genes in an Irish breast cancer cohort.

McInerney NM et al.

Breast Cancer Research and Treatment, 2010

Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles.

Seal S et al.

Nature Genetics, 2006

Evaluation of Fanconi Anemia genes in familial breast cancer predisposition.

Seal S et al.

Cancer Research, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."