Varaico: Literature-Extracted Genetic Variants

Gene:BRS3
Variant:p.R127Q
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BRS3

NM_001727.2:p.R127Q

Associated Papers

Constitutively active BRS3 is a genuinely orphan GPCR in placental mammals.

Tang H et al.

Plos Biology, 2019

Molecular basis for high affinity and selectivity of peptide antagonist, Bantag-1, for the orphan BB3 receptor.

Nakamura T et al.

Biochemical Pharmacology, 2016

Molecular basis for agonist selectivity and activation of the orphan bombesin receptor subtype 3 receptor.

Gonzalez N et al.

The Journal of Pharmacology and Experimental Therapeutics, 2008

Molecular cloning, genomic organization and selective expression of bombesin receptor subtype 3 in the sheep hypothalamus and pituitary.

Whitley JC et al.

Journal of Molecular Endocrinology, 1999

Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor.

Sainz E et al.

The Journal of Biological Chemistry, 1998

Identification of four amino acids in the gastrin-releasing peptide receptor that are required for high affinity agonist binding.

Akeson M et al.

The Journal of Biological Chemistry, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."