Varaico: Literature-Extracted Genetic Variants

Gene:BTG2
Variant:p.D105A
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BTG2

NM_006763.3:p.D105A

Associated Papers

Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach.

Bai Y et al.

Protein & Cell, 2015

The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex.

Doidge R et al.

Plos One, 2012

Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity.

Yang X et al.

Nucleic Acids Research, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."