Varaico: Literature-Extracted Genetic Variants

Gene:BTK
Variant:p.K12R
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BTK

NM_000061.3:p.K12R

Associated Papers

GESPA: classifying nsSNPs to predict disease association.

Khurana JK et al.

Bmc Bioinformatics, 2015

26206375 (PubMed )
Supplement: 12859_2015_673_MOESM2_ESM.xls › Sheet1

Molecular dynamic simulation to explore the molecular basis of Btk-PH domain interaction with Ins(1,3,4,5)P4.

Lu D et al.

Thescientificworldjournal, 2013

Molecular modeling studies of the Akt PH domain and its interaction with phosphoinositides.

Rong SB et al.

Journal of Medicinal Chemistry, 2001

Pleckstrin homology domains of tec family protein kinases.

Okoh MP et al.

Biochemical and Biophysical Research Communications, 1999

Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate.

Baraldi E et al.

Structure (london, England : 1993), 1999

BTKbase, mutation database for X-linked agammaglobulinemia (XLA).

Vihinen M et al.

Nucleic Acids Research, 1998

[XLA (X-linked agammaglobulinemia)].

Kato M et al.

Ryoikibetsu Shokogun Shirizu, 1998

Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia.

Hyvönen M et al.

The Embo Journal, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."