Varaico: Literature-Extracted Genetic Variants

Gene:BUB1B
Variant:p.E413K
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BUB1B

NM_001211.6:p.E413K

Associated Papers

BUB1B monoallelic germline variants contribute to prostate cancer predisposition by triggering chromosomal instability.

Silva MP et al.

Journal of Biomedical Science, 2024

A new enrichment approach for candidate gene detection in unexplained recurrent pregnancy loss and implantation failure.

Berkay EG et al.

Molecular Genetics and Genomics : Mgg, 2023

BUBR1 Pseudokinase Domain Promotes Kinetochore PP2A-B56 Recruitment, Spindle Checkpoint Silencing, and Chromosome Alignment.

Gama Braga L et al.

Cell Reports, 2020

BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling.

Overlack K et al.

Current Biology : Cb, 2017

Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells.

Prinz F et al.

The Journal of Biological Chemistry, 2016

An Inhibitor of PIDDosome Formation.

Thompson R et al.

Molecular Cell, 2015

The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing.

Lischetti T et al.

Nature Communications, 2014

Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.

Elowe S et al.

Journal of Cell Science, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."