Associated Papers
Pegcetacoplan in idiopathic and familial pediatric C3 glomerulopathy.
Román Ortiz E et al.
Pediatric Nephrology (berlin, Germany), 2025
Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study.
Brocklebank V et al.
Blood, 2023
37369098 (PubMed )
Supplement: BLOOD_BLD-2022-018833R2-mmc1.pdf
Functional characterization of 105 factor H variants associated with aHUS: lessons for variant classification.
Martín Merinero H et al.
Blood, 2021
The Relevance of the MCP Risk Polymorphism to the Outcome of aHUS Associated With C3 Mutations. A Case Report.
Lumbreras J et al.
Frontiers in Immunology, 2020
Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice.
Smith-Jackson K et al.
The Journal of Clinical Investigation, 2019
30714990 (PubMed )
Supplement: jci-129-99296-s152.pdf
Genotype-phenotype correlations of low-frequency variants in the complement system in renal disease and age-related macular degeneration.
Geerlings MJ et al.
Clinical Genetics, 2018
29888403 (PubMed )
Supplement: CGE-94-330-s001.zip › Appendix_S1 › Table_S4.xlsx › C3
Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.
Forneris F et al.
The Embo Journal, 2016
27013439 (PubMed )
Supplement: EMBJ-35-1133-s001.pdf
The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies.
Phillips EH et al.
Journal of Thrombosis and Haemostasis : Jth, 2016
The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome.
Martínez-Barricarte R et al.
Molecular Immunology, 2015
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