Associated Papers
C3 p.Asp1115Asn Variant-associated Atypical Hemolytic Uremic Syndrome with Spontaneous Remission Triggered by Influenza and COVID-19.
Fujino Y et al.
Internal Medicine (tokyo, Japan), 2025
The membrane attack complex drives thrombotic microangiopathy in complement mediated atypical hemolytic uremic syndrome.
Smith-Jackson K et al.
Kidney International, 2025
Late Onset Thrombotic Microangiopathy in Kidney Transplants; Poor Outcome Despite Eculizumab Treatment.
Glover EK et al.
Transplant International : Official Journal of the European Society for Organ Transplantation, 2025
Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study.
Brocklebank V et al.
Blood, 2023
Genetic variability shapes the alternative pathway complement activity and predisposition to complement-related diseases.
Rodríguez de Córdoba S
Immunological Reviews, 2023
Risk of Atypical HUS Among Family Members of Patients Carrying Complement Regulatory Gene Abnormality.
Ardissino G et al.
Kidney International Reports, 2021
A Novel Homozygous In-Frame Deletion in Complement Factor 3 Underlies Early-Onset Autosomal Recessive Atypical Hemolytic Uremic Syndrome - Case Report.
Pollack S et al.
Frontiers in Immunology, 2021
Exploiting the Autozygome to Support Previously Published Mendelian Gene-Disease Associations: An Update.
Maddirevula S et al.
Frontiers in Genetics, 2020
An Ex Vivo Test of Complement Activation on Endothelium for Individualized Eculizumab Therapy in Hemolytic Uremic Syndrome.
Galbusera M et al.
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation, 2019
Terminal complement effectors in atypical hemolytic uremic syndrome: C5a, C5b-9, or a bit of both?
Noris M et al.
Kidney International, 2019
Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice.
Smith-Jackson K et al.
The Journal of Clinical Investigation, 2019
Genotype-phenotype correlations of low-frequency variants in the complement system in renal disease and age-related macular degeneration.
Geerlings MJ et al.
Clinical Genetics, 2018
The lectin self of complement factor H.
Blaum BS
Current Opinion in Structural Biology, 2017
Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.
Forneris F et al.
The Embo Journal, 2016
The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies.
Phillips EH et al.
Journal of Thrombosis and Haemostasis : Jth, 2016
The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome.
Martínez-Barricarte R et al.
Molecular Immunology, 2015