Varaico: Literature-Extracted Genetic Variants

Gene:C5
Variant:p.C8Y
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C5

NM_001735.3:p.C8Y

Associated Papers

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Hadders MA et al.

Cell Reports, 2012

Structure of complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of membrane attack complex (MAC).

Aleshin AE et al.

The Journal of Biological Chemistry, 2012

Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.

Lovelace LL et al.

The Journal of Biological Chemistry, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."