Varaico: Literature-Extracted Genetic Variants

Gene:C5AR1
Variant:p.I124N
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C5AR1

NM_001736.4:p.I124N

Associated Papers

Conformational movement of F251 contributes to the molecular mechanism of constitutive activation in the C5a receptor.

Sen S et al.

Chemical Biology & Drug Design, 2008

Comparison of the retinitis pigmentosa mutations in rhodopsin with a functional map of the C5a receptor.

Hagemann IS et al.

Vision Research, 2006

Genetic analysis of the first and third extracellular loops of the C5a receptor reveals an essential WXFG motif in the first loop.

Klco JM et al.

The Journal of Biological Chemistry, 2006

Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site.

Higginbottom A et al.

The Journal of Biological Chemistry, 2005

Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor.

Whistler JL et al.

Traffic (copenhagen, Denmark), 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."