Associated Papers
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy.
Yang T et al.
Journal of Structural Biology, 2024
Submolecular probing of the complement C5a receptor-ligand binding reveals a cooperative two-site binding mechanism.
Dumitru AC et al.
Communications Biology, 2020
Third extracellular loop (EC3)-N terminus interaction is important for seven-transmembrane domain receptor function: implications for an activation microswitch region.
Rana S et al.
The Journal of Biological Chemistry, 2010
Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site.
Higginbottom A et al.
The Journal of Biological Chemistry, 2005
Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor.
Cain SA et al.
Biochemistry, 2001
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