Associated Papers
Cross-trait genomic modeling reveals the polygenic architecture and systemic impact of MASLD.
Du M et al.
Science Advances, 2026
Genetic Insights into Circulating Complement Proteins in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Potential Inflammatory Subgroup.
Maya J et al.
International Journal of Molecular Sciences, 2026
FCRL3 is an immunoregulatory receptor that restrains the activation of human memory T lymphocytes.
Bianchi N et al.
The Journal of Experimental Medicine, 2026
Restoration of PKM1 improves functional maturation of human stem-cell derived-β cell by regulating PEP metabolism.
Lin H et al.
Nature Communications, 2025
Human assembloids recapitulate periportal liver tissue in vitro.
Yuan L et al.
Nature, 2025
Depletion of individual dietary amino acids induce distinct metabolic and chromatin states.
Haws SA et al.
The Journal of Biological Chemistry, 2025
Proteolytic profiling of human plasma reveals an immunoactive complement C3 fragment.
Demir F et al.
The Embo Journal, 2025
Scalable and accurate rare variant meta-analysis with Meta-SAIGE.
Park E et al.
Nature Genetics, 2025
Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric central nervous system tumors.
Corbett RJ et al.
Nature Communications, 2025
SpliPath enhances disease gene discovery in case-control analyses of rare splice-altering genetic variants.
Wang Y et al.
Cell Reports Methods, 2025
Comprehensive and Site-Specific Characterization of Protein N-Glycosylation in AD Samples Reveals Its Potential Roles in Protein Aggregation and Synaptic Dysfunction.
Xu X et al.
Analytical Chemistry, 2025
Aberrant alternative splicing in alcoholic hepatitis: regulatory roles of RBPs and sQTLs.
Zhao J et al.
Bmc Gastroenterology, 2025
Spatial proteomics to discover aging-associated alterations in the renal tubulointerstitium.
Mun DG et al.
Clinical Proteomics, 2025
African Green Monkeys Respond to Synthetic Aβ Oligomers with Persistent Alzheimer's-like Activation.
Brown BRP et al.
Biorxiv : the Preprint Server for Biology, 2025
The NuRD component CHD3 promotes BMP signalling during cranial neural crest cell specification.
Mitchell ZH et al.
Embo Reports, 2025
Quantitative proteomics of formalin-fixed, paraffin-embedded cardiac specimens uncovers protein signatures of specialized regions and patient groups.
Achter JS et al.
Nature Cardiovascular Research, 2025
Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease.
Vromen EM et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2025
Myeloid-Derived Growth Factor-Regulated Oncogenesis in Lung Adenocarcinoma Is Associated with EGFR Status and Cancer Aggressiveness.
Hsiao TF et al.
Journal of Proteome Research, 2025
Neurodevelopmental origins of structural and psychomotor defects in CXCR4-linked primary immunodeficiency.
Demenego G et al.
Neuron, 2025
Common origin and somatic mutation patterns of composite lymphomas and leukemias.
Berg V et al.
Leukemia, 2025
Genetic Variants Affect Distinct Metabolic Pathways in Pediatric Multisystem Inflammatory Syndrome and Severe COVID-19.
Urbanski AH et al.
Journal of Medical Virology, 2025
Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric CNS tumors.
Corbett RJ et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy.
Wang YJ et al.
Science Translational Medicine, 2025
Advancing the Biochemical Understanding of Maple Syrup Urine Disease and the Impact of Liver Transplantation: A Pilot Study.
Fortis SP et al.
Journal of Proteome Research, 2025
Landscape of rare-allele variants in cultivated and wild soybean genomes.
Liu Z et al.
The Plant Genome, 2025
The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated-B Cells.
Chen Y et al.
Exploration (beijing, China), 2025
Genomic and immune profiling of breast cancer brain metastases.
Van Swearingen AED et al.
Acta Neuropathologica Communications, 2025
Human inborn errors of immunity: 2024 update on the classification from the International Union of Immunological Societies Expert Committee.
Poli MC et al.
Journal of Human Immunity, 2025
Genomic profiling of aggressive pathologic features in lung adenocarcinoma.
Lin YD et al.
Lung Cancer (amsterdam, Netherlands), 2025
Commander complex regulates lysosomal function and is implicated in Parkinson's disease risk.
Minakaki G et al.
Science (new York, N.y.), 2025
Comprehensive germline and somatic profiling of high-risk Thai breast cancer via next-generation sequencing.
Kamdee K et al.
Scientific Reports, 2025
Clinical exome sequencing for carrier screening in assisted reproductive technology and sperm donation.
Cai H et al.
Journal of Assisted Reproduction and Genetics, 2025
Genetic Terminal Complement Deficiency in Israeli Bedouins With Kidney Failure.
Chowers G et al.
Kidney International Reports, 2025
Approaches to Evaluate Whole Exome Sequencing Data That Incorporate Genetic Intolerance Scores for Congenital Anomalies, Including Intronic Regions Adjacent to Exons.
Taniguchi K et al.
Molecular Genetics & Genomic Medicine, 2025
Proteogenomic Profiling of Treatment-Naïve Metastatic Malignant Melanoma.
Kuras M et al.
Cancers, 2025
Human skeletal muscle fiber heterogeneity beyond myosin heavy chains.
Moreno-Justicia R et al.
Nature Communications, 2025
Rare and common single nucleotide variants in childhood-onset systemic lupus erythematosus.
Sayadi A et al.
Lupus Science & Medicine, 2025