Varaico: Literature-Extracted Genetic Variants

Gene:C8G
Variant:p.P3R
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C8G

NM_000606.3:p.P3R

Associated Papers

Genetic Insights into Circulating Complement Proteins in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Potential Inflammatory Subgroup.

Maya J et al.

International Journal of Molecular Sciences, 2026

41683992 (PubMed )
Supplement: ijms-27-01574-s001.zip › Supplementary_Tables_IJMS_Complement.xlsx › S9_Factor_D_Top_Hits

Mutations in sugar metabolism-related genes driving global drug-resistant Mycobacterium tuberculosis transmission revealed by whole-genome sequencing.

Li Y et al.

Bmc Infectious Diseases, 2026

Multiomics Mendelian randomization identifies serpin family G member 1 as a chronic obstructive pulmonary disease modulator.

Yi E et al.

Signal Transduction and Targeted Therapy, 2026

41559025 (PubMed )
Supplement: 41392_2025_2547_MOESM4_ESM.xlsx › Supplemental_Data_18

FCRL3 is an immunoregulatory receptor that restrains the activation of human memory T lymphocytes.

Bianchi N et al.

The Journal of Experimental Medicine, 2026

41091129 (PubMed )
Supplement: jem_20242474_datas2.xlsx › Imputed_Values

Spaceflight alters molecular networks linked to diverse human diseases in a single cellular model.

Al-Ahmadi W et al.

Science Advances, 2026

41481712 (PubMed )
Supplement: sciadv.adw7832_data_s1_to_s10.zip › adw7832_data_s3.xlsx › kegg

Restoration of PKM1 improves functional maturation of human stem-cell derived-β cell by regulating PEP metabolism.

Lin H et al.

Nature Communications, 2025

41423449 (PubMed )
Supplement: 41467_2025_67635_MOESM8_ESM.xlsx › Figure6B__right_Annotation__

Human assembloids recapitulate periportal liver tissue in vitro.

Yuan L et al.

Nature, 2025

41407857 (PubMed )
Supplement: 41586_2025_9884_MOESM7_ESM.zip › 2024-10-22623C-s7 › Supplementary_Dataset_3.xlsx › S10_GSEA_Hep_Tissue

Depletion of individual dietary amino acids induce distinct metabolic and chromatin states.

Haws SA et al.

The Journal of Biological Chemistry, 2025

41419194 (PubMed )
Supplement: mmc4.xlsx › Shared_EAA_DE_GO-BP_Enrichment

Integrated spatial proteomic analysis of breast cancer heterogeneity unravels cancer cell phenotypic plasticity.

Mardamshina M et al.

Nature Communications, 2025

41290667 (PubMed )
Supplement: 41467_2025_65477_MOESM6_ESM.xlsx › S4F

Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric central nervous system tumors.

Corbett RJ et al.

Nature Communications, 2025

41271695 (PubMed )
Supplement: 41467_2025_65190_MOESM12_ESM.xlsx › S10C_KEGG_pathways

Spatial proteomics to discover aging-associated alterations in the renal tubulointerstitium.

Mun DG et al.

Clinical Proteomics, 2025

41062932 (PubMed )
Supplement: 12014_2025_9550_MOESM2_ESM.xlsx › TableS2

African Green Monkeys Respond to Synthetic Aβ Oligomers with Persistent Alzheimer's-like Activation.

Brown BRP et al.

Biorxiv : the Preprint Server for Biology, 2025

41279249 (PubMed )
Supplement: media-1.zip › Tables › TableS1_Fragpipeoutput_Fig2.xlsx › Sheet_1-4_-_CSF_unique

Patients-Derived Organoids Sequencing-based FOXP4 Facilitates Radioresistance by Transcriptionally Modifying GPX4 to Regulate ferroptosis in Colorectal Cancer.

Chen Q et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2025

40789053 (PubMed )
Supplement: ADVS-12-e07080-s014.xlsx › Quant

Quantitative proteomics of formalin-fixed, paraffin-embedded cardiac specimens uncovers protein signatures of specialized regions and patient groups.

Achter JS et al.

Nature Cardiovascular Research, 2025

41006917 (PubMed )
Supplement: 44161_2025_721_MOESM5_ESM.xlsx › Sheet1

Disease-linked regulatory DNA variants and homeostatic transcription factors in epidermis.

Porter DF et al.

Nature Communications, 2025

40998781 (PubMed )
Supplement: 41467_2025_63070_MOESM8_ESM.xlsx › fdr_motif_changing

Protocadherin alpha gene cluster variants are potentially associated with short root anomaly in Japanese.

Ikeda-Sagawa Y et al.

European Journal of Orthodontics, 2025

40988636 (PubMed )
Supplement: cjaf065_supplementary_data.zip › Supplementary_Table__1_Clean_Copy_.xls › Sample3

Myeloid-Derived Growth Factor-Regulated Oncogenesis in Lung Adenocarcinoma Is Associated with EGFR Status and Cancer Aggressiveness.

Hsiao TF et al.

Journal of Proteome Research, 2025

40752010 (PubMed )
Supplement: pr5c00385_si_004.xlsx › MT-E-N

RENOVO-NF1 accurately predicts NF1 missense variant pathogenicity.

Bonetti E et al.

Human Genomics, 2025

40887659 (PubMed )
Supplement: 40246_2025_803_MOESM3_ESM.xlsx › Sheet_1

Integrative analysis of KEAP1/NFE2L2 alterations across 3600+ tumors reveals an NRF2 expression signature as a prognostic biomarker in cancer.

Crippa V et al.

Npj Precision Oncology, 2025

40825842 (PubMed )
Supplement: 41698_2025_1088_MOESM2_ESM.xlsx › STK11

Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric CNS tumors.

Corbett RJ et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

39974082 (PubMed )
Supplement: media-11.xlsx › S10C_KEGG_pathways

The MUC5B promoter variant results in proteomic changes in the nonfibrotic lung.

Herrera JA et al.

Jci Insight, 2025

40526433 (PubMed )
Supplement: jciinsight-10-189636-s112.xlsx › EpiOverlyingFF-IPFHC

Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma.

Kader T et al.

Cancer Discovery, 2025

39704522 (PubMed )
Supplement: cd-24-1366_supplementary_table_s9_suppst9.xlsx › BioProbeProperties

Comprehensive metabolomic and epigenomic characterization of microsatellite stable BRAF-mutated colorectal cancer.

Taira A et al.

Oncogene, 2025

40102611 (PubMed )
Supplement: 41388_2025_3326_MOESM7_ESM.xlsx › DESEq_results_BRAFmut_vs_WT_071

The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated-B Cells.

Chen Y et al.

Exploration (beijing, China), 2025

40585763 (PubMed )
Supplement: EXP2-5-270015-s003.xlsx › IgM-H.vs.Control

Deficits of Alzheimer's Disease Neuropsychological Architecture Correlate with Specific Exosomal mRNA Expression: Evidence of a Continuum?

Barceló E et al.

International Journal of Molecular Sciences, 2025

40430038 (PubMed )
Supplement: ijms-26-04897-s001.zip › Table_S4.xlsx › Sheet1

Human inborn errors of immunity: 2024 update on the classification from the International Union of Immunological Societies Expert Committee.

Poli MC et al.

Journal of Human Immunity, 2025

Biologically targeted discovery-replication scan identifies G×G interaction in relation to risk of Barrett's esophagus and esophageal adenocarcinoma.

Yan L et al.

Hgg Advances, 2025

39755942 (PubMed )
Supplement: mmc3.xlsx › D__Males_PartB

A Patient-Derived 3D Cyst Model of Polycystic Kidney Disease That Mimics Disease Development and Responds to Repurposing Candidates.

Meyer A et al.

Clinical and Translational Science, 2025

40235151 (PubMed )
Supplement: CTS-18-e70214-s001.xlsx › Mean__SD__N

The liver proteome of individuals with a natural UGT2B17 complete deficiency.

Rouleau M et al.

Scientific Reports, 2025

39953065 (PubMed )
Supplement: 41598_2025_89160_MOESM2_ESM.xlsx › S1._Identified_and_DE_proteins

HPV integration in head and neck cancer: downstream splicing events and expression ratios linked with poor outcomes.

Li S et al.

Biorxiv : the Preprint Server for Biology, 2025

39896613 (PubMed )
Supplement: media-7.xlsx › HPVint____versus_HPVint_-_

A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia.

Dong Z et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

39752521 (PubMed )
Supplement: pnas.2413302121.sd03.xlsx › binder_wt_vs_ctrl_res

Integrated proteogenomic characterization of ampullary adenocarcinoma.

Zhang Q et al.

Cell Discovery, 2025

39762212 (PubMed )
Supplement: 41421_2024_742_MOESM4_ESM.xlsx › Supplenebtary_Table_4b

A proteotranscriptomic approach to dissect the molecular landscape of human retinoblastoma.

Wolf J et al.

Frontiers in Oncology, 2025

40395327 (PubMed )
Supplement: Table2.xlsx › Sheet1
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."