Varaico: Literature-Extracted Genetic Variants

Gene:CALR
Variant:p.K368fs
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CALR

NM_004343.4:p.K368fs

Associated Papers

CALR Type 1-Like Mutations Increase Endoplasmic Reticulum Free Ca2+ and Induce ERK1/2 Activation Independent of Thrombopoietin Receptor Activation.

Faiz M et al.

Cell Biology International, 2025

40586641 (PubMed )
Supplement: CBIN-49-1262-s001.docx

High-resolution melting assay for rapid, simultaneous detection of JAK2, MPL and CALR variants.

Sande CM et al.

Journal of Clinical Pathology, 2024

Diagnosis- and Prognosis-Related Gene Alterations in BCR::ABL1-Negative Myeloproliferative Neoplasms.

Morishita S et al.

International Journal of Molecular Sciences, 2023

37629188 (PubMed )
Supplement: ijms-24-13008-s001.zip › ijms-2555672-supplementary.pdf

Clinical Characteristics and Outcomes of Patients with Primary and Secondary Myelofibrosis According to the Genomic Classification Using Targeted Next-Generation Sequencing.

Garrote M et al.

Cancers, 2023

37568719 (PubMed )
Supplement: cancers-15-03904-s001.zip › cancers-2478235-supplementary.pdf

ASXL1 mutations accelerate bone marrow fibrosis via EGR1-TNFA axis-mediated neoplastic fibrocyte generation in myeloproliferative neoplasms.

Shi Z et al.

Haematologica, 2023

36005555 (PubMed )
Supplement: 2021_280320_SHI_SUPPL.pdf

Effects of CALR-Mutant Type and Burden on the Phenotype of Myeloproliferative Neoplasms.

Kim HY et al.

Diagnostics (basel, Switzerland), 2022

Targeting human CALR-mutated MPN progenitors with a neoepitope-directed monoclonal antibody.

Tvorogov D et al.

Embo Reports, 2022

35156745 (PubMed )
Supplement: EMBR-23-e52904-s006.pdf

Mutational spectrum and prognosis in Chinese patients with prefibrotic primary myelofibrosis.

Cheng CK et al.

Ejhaem, 2022

35846205 (PubMed )
Supplement: JHA2-3-184-s002.xlsx › All_MPN_cases

CALR-ETdb, the database of calreticulin variants diversity in essential thrombocythemia.

El Jahrani N et al.

Platelets, 2022

Myeloproliferative neoplasm-driving Calr frameshift promotes the development of pulmonary hypertension in mice.

Minakawa K et al.

Journal of Hematology & Oncology, 2021

33785036 (PubMed )
Supplement: 13045_2021_1064_MOESM7_ESM.pdf

INDELseek: detection of complex insertions and deletions from next-generation sequencing data.

Au CH et al.

Bmc Genomics, 2017

Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution.

Cabagnols X et al.

Leukemia, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."