Varaico: Literature-Extracted Genetic Variants

Gene:CARD8
Variant:p.S10R
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CARD8

NM_001184900.3:p.S10R

Associated Papers

Association between C10X polymorphism in the CARD8 gene and inflammatory markers in young healthy individuals in the LBA study.

Fransén K et al.

Bmc Cardiovascular Disorders, 2024

NF-κB-94ins/del ATTG Genotype Contributes to the Susceptibility and Imbalanced Th17 Cells in Patients with Immune Thrombocytopenia.

Yu J et al.

Journal of Immunology Research, 2018

Polymorphism in the NLRP3 inflammasome-associated EIF2AK2 gene and inflammatory bowel disease.

Varghese GP et al.

Molecular Medicine Reports, 2015

Association between CARD8 rs2043211 polymorphism and inflammatory bowel disease: a meta-analysis.

Liu J et al.

Immunological Investigations, 2015

CARD8 rs2043211 polymorphism is associated with gout in a Chinese male population.

Chen Y et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2015

Is the CARD8 rs2043211 polymorphism associated with susceptibility to Crohn's disease? A meta-analysis.

Zhang ZT et al.

Autoimmunity, 2015

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.

Mathews RJ et al.

Annals of the Rheumatic Diseases, 2014

[Association between AXIN2 polymorphism and oligodontia].

Wong S et al.

Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences, 2014

CARD8 is a negative regulator for NLRP3 inflammasome, but mutant NLRP3 in cryopyrin-associated periodic syndromes escapes the restriction.

Ito S et al.

Arthritis Research & Therapy, 2014

CARD8 gene encoding a protein of innate immunity is expressed in human atherosclerosis and associated with markers of inflammation.

Paramel GV et al.

Clinical Science (london, England : 1979), 2013

CARD8 rs2043211 (p.C10X) polymorphism is not associated with disease susceptibility or cardiovascular events in Spanish rheumatoid arthritis patients.

García-Bermúdez M et al.

Dna and Cell Biology, 2013

Cytokine profile in a cohort of healthy blood donors carrying polymorphisms in genes encoding the NLRP3 inflammasome.

Sahdo B et al.

Plos One, 2013

Association study of CARD8 (p.C10X) and NLRP3 (p.Q705K) variants with rheumatoid arthritis in French and Tunisian populations.

Ben Hamad M et al.

International Journal of Immunogenetics, 2012

Association of CARD8 with inflammatory bowel disease in Koreans.

Yang SK et al.

Journal of Human Genetics, 2011

Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease.

Roberts RL et al.

Genes and Immunity, 2010

CARD8 p.C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis.

Kastbom A et al.

Annals of the Rheumatic Diseases, 2010

No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts.

Büning C et al.

Inflammatory Bowel Diseases, 2008

Deficiency of the NF-kappaB inhibitor caspase activating and recruitment domain 8 in patients with rheumatoid arthritis is associated with disease severity.

Fontalba A et al.

Journal of Immunology (baltimore, Md. : 1950), 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."