Associated Papers
Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract.
Wu H et al.
Cancer Communications (london, England), 2022
36264285 (PubMed )
Supplement: CAC2-42-1367-s002.xlsx › Supplementary_Table_S3
Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo.
Reinke S et al.
Cell Reports, 2020
Multiple Sclerosis patients carry an increased burden of exceedingly rare genetic variants in the inflammasome regulatory genes.
Vidmar L et al.
Scientific Reports, 2019
31235738 (PubMed )
Supplement: 41598_2019_45598_MOESM2_ESM.xlsx › Sheet1
Current knowledge on procaspase-1 variants with reduced or abrogated enzymatic activity in autoinflammatory disease.
Luksch H et al.
Current Rheumatology Reports, 2015
Human procaspase-1 variants with decreased enzymatic activity are associated with febrile episodes and may contribute to inflammation via RIP2 and NF-κB signaling.
Heymann MC et al.
Journal of Immunology (baltimore, Md. : 1950), 2014
Naturally occurring genetic variants of human caspase-1 differ considerably in structure and the ability to activate interleukin-1β.
Luksch H et al.
Human Mutation, 2013
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