Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.L194F
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CASP3

NM_004346.4:p.L194F

Associated Papers

ERα determines the chemo-resistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressions.

He YH et al.

Molecular Therapy. Nucleic Acids, 2021

34589276 (PubMed )
Supplement: mmc2.pdf

Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis.

Wang YL et al.

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology, 2020

Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants.

Giorgi C et al.

Frontiers in Oncology, 2016

Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF).

Tan BS et al.

Cell Death & Disease, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."