Associated Papers
Microfluidic deep mutational scanning of the human executioner caspases reveals differences in structure and regulation.
Roychowdhury H et al.
Cell Death Discovery, 2022
Abnormal Microglia and Enhanced Inflammation-Related Gene Transcription in Mice with Conditional Deletion of Ctcf in Camk2a-Cre-Expressing Neurons.
McGill BE et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2018
Doxorubicin induces caspase-mediated proteolysis of KV7.1.
Strigli A et al.
Communications Biology, 2018
Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.
Walters J et al.
Archives of Biochemistry and Biophysics, 2011
A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis.
Walters J et al.
The Biochemical Journal, 2009
Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3.
Feeney B et al.
Biochemistry, 2006
Mutations in the procaspase-3 dimer interface affect the activity of the zymogen.
Pop C et al.
Biochemistry, 2003
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