Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.D28A
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CASP3

NM_004346.4:p.D28A

Associated Papers

Doxorubicin induces caspase-mediated proteolysis of KV7.1.

Strigli A et al.

Communications Biology, 2018

Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.

Walters J et al.

Archives of Biochemistry and Biophysics, 2011

A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis.

Walters J et al.

The Biochemical Journal, 2009

Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3.

Feeney B et al.

Biochemistry, 2006

Mutations in the procaspase-3 dimer interface affect the activity of the zymogen.

Pop C et al.

Biochemistry, 2003

Characterization of the apoptosis suppressor protein P49 from the Spodoptera littoralis nucleopolyhedrovirus.

Pei Z et al.

The Journal of Biological Chemistry, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."